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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261110T110000
DTEND;TZID=Europe/Paris:20261110T120000
DTSTAMP:20261104T204118Z
CREATED:20261104T204032Z
LAST-MODIFIED:20261104T204118Z
UID:10000348-1794308400-1794312000@sfp-alpes.fr
SUMMARY:Alexandra COLIN (IRIG\, CEA\, Grenoble\, France)
DESCRIPTION:Dynamics and  scaling of competitive actin architectures\nRésumé : \nCells constantly experience environmental changes requiring a fast adaptation of their different actin structures. However\, the mechanisms governing the size and dynamics of these multiple actin structures remain unknown. Decoupling the various parameters that would provide a complete understanding of these mechanisms is very complicated in a cellular context. This is why we have developed a bottom-up approach to identify the key molecular mechanisms that determine the size and coexistence of multiple competing actin architectures. We used a reconstituted system consisting of purified proteins and substrates to localize actin polymerization in microwells\, enabling us to work with a limited number of components. With this system\, we reconstituted several dynamic actin architectures\, competing for a limited pool of protein\, over a period of multiple hours. This allowed us to gain key insights into physiological functions related to actin turnover. I will show how we used this system to study the limits of scaling in dynamic structures\, as well as the limits of coexistence in actin networks under resource-limited conditions. Finally\, I will show how we can recapitulate these results in a complementary cellular system\, in which we have demonstrated that an increase in spreading area leads to a decrease in overall turnover\, due to a predominance of structures with low turnover. \n_ \nContact : olivier.destaing@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/alexandra-colin-irig-cea-grenoble-france/
LOCATION:IAB – Salle de séminaire\, IAB Site Santé - Allée des Alpes\, La Tronche\, 38700\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IAB":MAILTO:appaixfl@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261110T140000
DTEND;TZID=Europe/Paris:20261110T150000
DTSTAMP:20261102T230313Z
CREATED:20261102T230313Z
LAST-MODIFIED:20261102T230313Z
UID:10000340-1794319200-1794322800@sfp-alpes.fr
SUMMARY:Francisco YUBERO (Instituto de Ciencia de Materiales de Sevilla (CSIC – Univ. Sevilla)\, Spain)
DESCRIPTION:Porous thin film technology @ ICMS\nRésumé : \nIn this presentation\, I will show a survey of technical and scientific developments of our research group in the last years at the Institute of Materials Science of Seville. I will share our experience growing porous and compact thin films by physical vapor deposition methods\, as well as their performance in a variety of technological applications such as ophthalmic and electrochromic coatings\, dichroic filters\, scintillators\, optofluidic and electrochemical sensors or electrodes for solid oxide fuel cells or water electrolysers.  Thus\, for example\, I will address some studies related to proof of concept experiences to show enhanced absorption of dye solutions in porous Bragg microcavities or the development of refractometric liquid and vapor sensing transducers based on porous multilayers fabricated by glancing angle deposition approach.  I will also share our latest work on catalysts for green hydrogen production in anion exchange membrane water electrolysis\, as well as\, results on the scaling up of our technology for devices with sizes relevant for industrial implementation. \nShort Bio/CV \nPhD In this presentation\, I will show a survey of technical and scientific developments of our research group in the last years at the Institute of Materials Science of Seville. I will share our experience growing porous and compact thin films by physical vapor deposition methods\, as well as their performance in a variety of technological applications such as ophthalmic and electrochromic coatings\, dichroic filters\, scintillators\, optofluidic and electrochemical sensors or electrodes for solid oxide fuel cells or water electrolysers.  Thus\, for example\, I will address some studies related to proof of concept experiences to show enhanced absorption of dye solutions in porous Bragg microcavities or the development of refractometric liquid and vapor sensing transducers based on porous multilayers fabricated by glancing angle deposition approach.  I will also share our latest work on catalysts for green hydrogen production in anion exchange membrane water electrolysis\, as well as\, results on the scaling up of our technology for devices with sizes relevant for industrial implementation. \n_ \nContact : deborah.verger@grenoble-inp.fr
URL:https://sfp-alpes.fr/event/francisco-yubero-instituto-de-ciencia-de-materiales-de-sevilla-csic-univ-sevilla-spain/
LOCATION:LMGP – salle des séminaires\, Grenoble INP -Phelma 3 parvis Louis Néel\, Grenoble\, 38054\, France
CATEGORIES:Séminaire
ORGANIZER;CN="LMGP":MAILTO:deborah.verger@grenoble-inp.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261110T140000
DTEND;TZID=Europe/Paris:20261110T150000
DTSTAMP:20261101T223942Z
CREATED:20261101T223658Z
LAST-MODIFIED:20261101T223942Z
UID:10000328-1794319200-1794322800@sfp-alpes.fr
SUMMARY:Ivan AMELIO (Unversity of Ghent)
DESCRIPTION:Quantum simulation with Fluxonium Qutrit Arrays\nRésumé : \nFluxonium superconducting circuits were originally proposed to realize highly coherent qubits. In this talk\, we explain how these circuits can be used to implement and harness qutrits\, by tuning their energy levels and matrix elements via an external flux bias. In particular\, we investigate arrays of fluxonium qutrits\, and their potential for the quantum simulation of exotic quantum matter. We identify different operational regimes\, classified according to the plasmon-like versus fluxon-like nature of the qutrit excitations. Highly tunable on-site interactions are complemented by correlated single-particle hopping\, pair hopping and non-local interactions\, which naturally emerge and have different weights in the different regimes. We investigate the rich ground-state phase diagram of qutrit arrays and propose practical dynamical experiments to probe the different regimes. Future directions towards analogue simulation of exotic quantum matter are presented. \n_ \nContact : equipe-seminaires-nano@listes.grenoble.cnrs.fr
URL:https://sfp-alpes.fr/event/ivan-amelio-unversity-of-ghent/
LOCATION:CNRS – Salle Rémy Lemaire (K223)\, CNRS - Institut Néel 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261112T080000
DTEND;TZID=Europe/Paris:20261112T090000
DTSTAMP:20261023T092824Z
CREATED:20261023T092824Z
LAST-MODIFIED:20261023T092824Z
UID:10000320-1794470400-1794474000@sfp-alpes.fr
SUMMARY:Mathieu VAILLANT (service : Neurologie)
DESCRIPTION:Hypnose thérapeutique et douleur lors des ponctions lombaires : étude randomisée\n_ \nContact : sante-communication@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/mathieu-vaillant-service-neurologie/
LOCATION:CHU – Salle Gilbert Faure\, CHU Grenoble Alpes Pavillon Vercors (côté Belledonne)\, La Tronche\, 38043\, France
CATEGORIES:Séminaire
ORGANIZER;CN="CHU Grenoble":MAILTO:sante-communication@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261112T130000
DTEND;TZID=Europe/Paris:20261112T140000
DTSTAMP:20261102T231313Z
CREATED:20261102T231313Z
LAST-MODIFIED:20261102T231313Z
UID:10000341-1794488400-1794492000@sfp-alpes.fr
SUMMARY:Annabelle BALLESTA (Institut Curie\, Paris)
DESCRIPTION:Systems pharmacology and machine learning for optimizing treatments of brain tumors\nRésumé : \nGlioblastoma (GBM)\, the most frequent and aggressive brain tumor inadults\, is associated with a dismal prognostic despite intensive treatment involving surgery\, radiotherapy and temozolomide (TMZ)-based chemotherapy. The initial or acquired resistance of GBM to TMZ appeals for precision medicine approaches for the design of novel efficient\ncombination pharmacotherapies. To that end\, a comprehensive approach combining quantitative systems pharmacology (QSP) and machine learning was undertaken to design TMZ-based drug combinations circumventing the initial resistance to the alkylating agent. A QSP model representing TMZ cellular pharmacokinetics- pharmacodynamics and dysregulated pathways in GBM based on ordinary differential equations was developed and validated using multi-type time- and dose-resolved datasets. In silico drug screening based on numerical optimization and subsequent experimental validation identified a strategy to re-sensitize TMZ-resistant cells consisting in combining TMZ with inhibitors of the base excision repair and of homologous recombination. Using machine learning\, model parameters driving response to such optimal multi-agent therapy were derived to assist decision making in patients. Thus\, we successfully demonstrated the relevance of combined QSP and machine learning to design efficient drug combinations re-sensitizing glioblastoma cells initially resistant to TMZ. The developed framework may further serve to identify personalized therapies and administration schedules by extending it to account for additional patient-specific altered pathways and whole-body features. \n_ \nContact : antoine.frenoy@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/annabelle-ballesta-institut-curie-paris/
LOCATION:IMAG – Salle de Réunion\, 150 place du Torrent\, St Martin d’Hères\, 38400\, France
CATEGORIES:Séminaire
ORGANIZER;CN="TIMC - IMAG":MAILTO:lucie.lamothe@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261112T140000
DTEND;TZID=Europe/Paris:20261112T150000
DTSTAMP:20261101T230400Z
CREATED:20261101T230243Z
LAST-MODIFIED:20261101T230400Z
UID:10000331-1794492000-1794495600@sfp-alpes.fr
SUMMARY:Hélène CASTEBRUNET (maître de conférence UGA) & Gérémy PANTHOU (physicien-adjoint CNAP à l’Institut des Géosciences de l’Environnement (Grenoble))
DESCRIPTION:Eau dans le Y Grenoblois : reste-t-il une seule goutte qui n’ait pas été impactée par les activités humaines ?\nRésumé : \nA venir… \n_ \nContact : yvonne.soldo@neel.cnrs.fr
URL:https://sfp-alpes.fr/event/helene-castebrunet-maitre-de-conference-uga-geremy-panthou-physicien-adjoint-cnap-a-linstitut-des-geosciences-de-lenvironnement-grenoble-2/
LOCATION:CNRS – Bâtiment A\, CNRS - Institut Néel 25 avenue des Martyrs\, Grenoble\, 38054\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261112T140000
DTEND;TZID=Europe/Paris:20261112T150000
DTSTAMP:20261023T142909Z
CREATED:20261023T142909Z
LAST-MODIFIED:20261023T142909Z
UID:10000323-1794492000-1794495600@sfp-alpes.fr
SUMMARY:Pierre PUJOL (LPT\, Univ. Toulouse)
DESCRIPTION:Skyrmions\, bimerons and their effect on itinerant electrons\nRésumé : \nMagnetic skyrmions and bimerons are topological spin textures that exhibit remarkable stability at finite temperatures. In this talk we will discuss a variety of models exhibiting different phases (fluid and crystallines) of these topological spin textures that are tunable with temperature\, magnetic field or strain. We’ll also discuss their effect on itinerant electrons\, and in particular the presence of bound states and one dimensional (i.e.\, like edge) electronic transport. \n_ \nContact : elsa.lhotel@neel.cnrs.fr
URL:https://sfp-alpes.fr/event/pierre-pujol-lpt-univ-toulouse/
LOCATION:CNRS – Salle Rémy Lemaire (K223)\, CNRS - Institut Néel 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261113T093000
DTEND;TZID=Europe/Paris:20261113T113000
DTSTAMP:20261102T214525Z
CREATED:20261102T214525Z
LAST-MODIFIED:20261102T214525Z
UID:10000332-1794562200-1794569400@sfp-alpes.fr
SUMMARY:Soutenance de thèse par Preslav SMITS (DCM (équipe CIRe))
DESCRIPTION:Redox properties of free N-Heterocyclic Carbenes\n_ \nContact : nathalie.camerino@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/soutenance-de-these-par-preslav-smits-dcm-equipe-cire/
LOCATION:DCM – Salle C209\, DCM - Bât Chimie Recherche 301 rue de la Chimie\, St Martin d'Hères\, 38400\, France
CATEGORIES:Soutenance,Soutenance de Thèse
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261113T110000
DTEND;TZID=Europe/Paris:20261113T120000
DTSTAMP:20261106T132237Z
CREATED:20261103T215003Z
LAST-MODIFIED:20261106T132237Z
UID:10000342-1794567600-1794571200@sfp-alpes.fr
SUMMARY:Budhaditya BHATTACHARJEE (University of Luxembourg)
DESCRIPTION:Mechanisms for Chaotic Transitions in Many-Body Systems\nLe séminaire théorie est financé par la fédération de recherche Quantalps. \nRésumé : \nA widely observed phenomenon in interacting systems of many particles is a phase transition from a chaotic to an integrable/non-chaotic phase and vice versa. The mechanism which controls such a transition is strongly model-dependent. It is therefore necessary to develop a model of such chaotic transitions which picks up the model-independent features and explains the nature of the transition. I will present and discuss two potential mechanisms which describe such transitions. The first mechanism\, titled « network classes » addresses integrable-to-chaotic transitions and separates systems into universality classes. Inspired from classical dynamics\, I will extend its’ definition to quantum systems. In the process\, I will also introduce quantum analogues of known classical chaos markers. I will discuss where such a description works and where it fails through a quantum—classical correspondence. Then I will present the next mechanism\, titled « scale separation » which will address chaotic-to-integrable transitions. I will discuss it purely in a quantum setup by constructing a (semi=solvable) model which explicitly realizes this mechanism. I will present the various properties of this model show how such a transition may occur. I will conclude with comments and future directions on developing better descriptions of such transitions. \n_ \nContact : loic.herviou@lpmmc.cnrs.fr \n 
URL:https://sfp-alpes.fr/event/budhaditya-bhattacharjee-university-of-luxembourg/
LOCATION:LPMMC – salle Roger Maynard (G421)\, CNRS - LPMMC 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261113T143000
DTEND;TZID=Europe/Paris:20261113T163000
DTSTAMP:20261102T224038Z
CREATED:20261102T224038Z
LAST-MODIFIED:20261102T224038Z
UID:10000337-1794580200-1794587400@sfp-alpes.fr
SUMMARY:Soutenance de thèse par Nathan BUJAULT (Institut Néel)
DESCRIPTION:Impact des perturbations sur les glace de spins : Effets quantiques & Fragmentation / Impact of perturbations on spin ices : Quantum Effects & Fragmentation\nRésumé : \nLe magnétisme frustré est un domaine de la physique de la matière condensée qui étudie les systèmes où les interactions entre moments magnétiques ne peuvent pas être satisfaites simultanément\, du fait de la géométrie du réseau cristallin ou de la nature même des interactions\, générant ainsi une pléthore de nouveaux états exotiques. Parmi ceux-ci\, la glace de spins est un état corrélé et dégénéré\, sans ordre à longue portée\, qui est gouverné par une contrainte locale (règle de la glace) émanant des interactions ferromagnétiques effectives. Dans les oxydes de terre rare de formule R2M2O7 (R = terre rare\, M = métal)\, la terre rare occupe un réseau pyrochlore\, archétype du réseau frustré tridimensionnel\, et l’état glace de spins est stabilisé lorsque R = Ho\, Dy et M est non magnétique. Cette thèse a pour objectif de comprendre comment cet état fondamental évolue sous l’effet de perturbations\, à travers deux stratégies complémentaires : (i) Par l’introduction d’un désordre structural en substituant partiellement les atomes de Ti par des atomes de Hf dans Ho2Ti2O7. Hf étant de taille plus importante\, cette substitution introduit une distorsion locale du réseau cristallin\, qui promeut l’émergence de fluctuations quantiques sous la forme de champs transverses. Ces fluctuations peuvent induire un effet tunnel entre les différentes configurations dégénérées de l’état fondamental et stabiliser une nouvelle phase\, la glace de spins quantique\, dans laquelle de nouvelles excitations sont attendues. A travers une étude détaillée d’échantillons sous forme de poudre présentant plusieurs taux de substitutions\, nous étudions comment l’état glace de spins et ses propriétés évoluent avec le désordre. Nous montrons le développement de fluctuations quantiques sous l’effet de la substitution par l’observation d’une accélération globale de la dynamique ainsi que la présence de nouvelles excitations à basse énergie. Les conséquences de ces observations sur la nature des phases stabilisées est discutée. (ii) Par l’introduction d’un métal magnétique sur le site M qui génère une interaction magnétique entre la terre rare et le métal et altère profondément l’état fondamental. Lorsque M = Ir\, des études antérieures ont montré la stabilisation d’un état fragmenté dans lequel l’aimantation est constituée d’une composante ordonnée antiferromagnétique et d’une composante désordonnée régie par une contrainte locale. Nous nous intéressons ici au cas du Ru pour vérifier l’hypothèse d’un état fragmenté cette fois de type ferromagnétique dans le composé Ho2Ru2O7. Pour ce faire\, nous étudions les composés Y2Ru2O7 et Dy2Ru2O7. Dans Y2Ru2O7\, la dépendance en température de la structure magnétique du ruthénium et des ondes de spins associées sont mesurées dans l’objectif d’établir le Hamiltonien des interactions du ruthénium. Dans Dy2Ru2O7\, nous montrons que bien que le moment ordonné soit différent de celui observé dans Ho2Ru2O7\, la dynamique mesurée possède des caractéristiques similaires. Ces observations questionnent les mécanismes d’interactions entre la terre rare et le métal\, ce que nous abordons en sondant la dépendance en température de la structure énergétique des niveaux de champ cristallin. Ces travaux s’appuient essentiellement sur des mesures d’aimantation et de susceptibilité alternative à très basse température (70 mK) effectuées sur des magnétomètres développés au laboratoire combinées à un vaste panel de mesures de diffusion neutronique (diffraction\, neutrons polarisés\, diffusion inélastique\, écho de spin). \nAbstract : \nFrustrated magnetism is a field of condensed matter physics that studies systems in which the interactions between\nmagnetic moments cannot be satisfied simultaneously\, due to the geometry of the crystal lattice or the very nature of the interactions\, thereby generating a plethora of new exotic states. Among these\, spin ice is a correlated and degenerate state\, lacking long-range order\, which is governed by a local constraint (the ice rule) arising from effective ferromagnetic interactions. In rare-earth oxides with formula R2M2O7 (R = rare earth\, M = metal)\, the rare earth lies on a pyrochlore lattice—the archetype of a three-dimensional frustrated lattice—and the spin ice state is stabilized when R = Ho\, Dy\, and M is nonmagnetic. The objective of this thesis is to understand how this ground state evolves under the influence of perturbations\, using two complementary strategies: (i) The introduction of structural disorder through the partial substitution of Ti atoms with Hf atoms in Ho2Ti2O7. Since Hf atoms are larger\, this substitution introduces a local distortion of the crystal lattice\, which promotes the emergence of quantum fluctuations in the form of transverse fields. These fluctuations can induce a tunneling effect between the various degenerate configurations of the ground state and stabilize a new quantum spin ice phase in which new excitations are expected. Through a detailed study of powder samples with various substitution rates\, we investigate how the spin ice state and its properties evolve with disorder. We demonstrate the development of quantum fluctuations induced by substitution by observing a global acceleration of the dynamics as well as the presence of new low energy excitations. The implications of these observations for the nature of the stabilized phases are discussed. (ii) The introduction of a magnetic metal on the M site\, which generates a magnetic interaction between the rare earth and the metal and deeply alters the ground state. When M = Ir\, previous studies have shown the stabilization of a fragmented state in which the magnetization consists of an ordered antiferromagnetic component and a disordered component governed by local constraints. Here\, we focus on the case of Ru to test the hypothesis of a fragmented state\, this time of the ferromagnetic type\, in the compound Ho2Ru2O7. To this end\, we study the Y2Ru2O7 and Dy2Ru2O7 compounds. In Y2Ru2O7\, the temperature dependence of the magnetic structure of ruthenium and the associated spin waves are measured with the aim of establishing the Hamiltonian for ruthenium interactions. In Dy2Ru2O7\, we show that although the ordered moment differs from that observed in Ho2Ru2O7\, the measured dynamics exhibit similar characteristics. These observations raise questions about the interaction mechanisms between the rare earth element and the metal\, which we address by probing the temperature dependence of the energy structure of the crystal field levels. This research is based primarily on measurements of magnetization and alternative susceptibility at very low temperatures (70 mK) performed using magnetometers developed in the laboratory\, combined with a wide range of neutron scattering measurements (diffraction\, polarized neutrons\, inelastic scattering\, and spin echo). \n_ \nContact : nathan.bujault@neel.cnrs.fr
URL:https://sfp-alpes.fr/event/soutenance-de-these-par-nathan-bujault-institut-neel/
LOCATION:CNRS – Bâtiment A\, CNRS - Institut Néel 25 avenue des Martyrs\, Grenoble\, 38054\, France
CATEGORIES:Soutenance,Soutenance de Thèse
END:VEVENT
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