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DTSTART;TZID=Europe/Paris:20261127T140000
DTEND;TZID=Europe/Paris:20261127T160000
DTSTAMP:20261015T150904Z
CREATED:20261015T150904Z
LAST-MODIFIED:20261015T150904Z
UID:10000309-1795788000-1795795200@sfp-alpes.fr
SUMMARY:Soutenance de thèse par Alessio D’ACAPITO (CEA-Irig/IBS)
DESCRIPTION:Study of E. Coli cell wall perforation by bacteriophage T5\nRésumé : \nBacteriophages are fascinating nanomachines that are highly specific and remarkably efficient in infecting their bacterial hosts. While the cell envelope perforation mechanisms by myophages\, such as T4 or of podophages\, such as P22 has been well characterized\, less is known about the molecular mechanisms of the infection of siphophages\, such as T5. \nIn this work\, we used an integrative approach combining cryo-electron tomography (cryo-ET)\, subtomogram averaging (STA) and single particle analysis (SPA) to obtain snapshots at successive stages of phage T5 infection\, from early cell recognition to post DNA injection state. We used E. coli minicells as a simplified cellular model and developed a tailored grid preparation protocol to control the timings of infection and focus on specific timepoints. \nFirst\, we solved the structure of T5 L-shaped fibers at 4Å resolution by SPA. Second\, we characterized by SPA the structure of the adsorbed but noninfecting phage at 4°C by describing a new intermediate of the tube anchoring mechanism\, where the tail tube is brought close to the membrane by the bending of the central fiber but the tube is still closed ; we could conclude that the Cterminal part of the tape measure protein (TMP) pb2-C plays a key structural role. \nLastly\, we solved by STA the structure of the infecting phage tip docked on the minicell and of the trans-periplasmic channel that allows the DNA to be translocated into the bacterial cytosol. We propose a model for the channel\, formed of three copies of the TMP. \nBeyond structural biology\, my PhD work was also focused on building tools for the cryo-ET local community. I have developed a tool for “erasing” the membrane signal from sub-volumes extracted with Dynamo as well as a beginner-friendly method for quick tomogram reconstruction from raw data. We made both publicly available on GitHub.​ ​​​​ \n_ \nLes séminaires et soutenances sont ouverts à tous\, notez toutefois que l’accès au campus EPN nécessite un avis de rendez-vous. Merci de remplir ce formulaire  et de l’adresser\, plus de 48h à l’avance\, à ce contact. \n\n\nPensez à vous munir d’une pièce d’identité le jour de votre visite.
URL:https://sfp-alpes.fr/event/soutenance-de-these-par-alessio-dacapito-cea-irig-ibs/
LOCATION:IBS – Salle des séminaires\, IBS 71 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Soutenance,Soutenance de Thèse
ORGANIZER;CN="IBS":MAILTO:ibs.seminaires@ibs.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261201T140000
DTEND;TZID=Europe/Paris:20261201T150000
DTSTAMP:20261015T135646Z
CREATED:20261015T135646Z
LAST-MODIFIED:20261015T135646Z
UID:10000306-1796133600-1796137200@sfp-alpes.fr
SUMMARY:Valeria DEL CAMPO (Physics Department\, Universidad Técnica Federico Santa María\, Chile)
DESCRIPTION:Graphene in photovoltaic solar energy : results and challenges\nRésumé : \nGraphene has attracted significant interest in photovoltaic applications due to its unique combination of high electrical conductivity\, optical transparency\, mechanical flexibility\, and chemical stability. Despite these advantages\, several scientific and technological challenges still limit its integration into high-performance solar cells. This seminar presents recent results from our research group on the use of graphene in different photovoltaic technologies\, with particular emphasis on the role of interfaces and surface electronic properties. \nFirst\, the implementation of graphene as a transparent conductive electrode in silicon heterojunction (SHJ) solar cells will be discussed. In this context\, graphene offers a promising alternative to conventional transparent conductive oxides\, while enabling new device architectures. The second part of the talk will focus on the use of graphene as an encapsulation layer to stabilize copper oxide hole-transport layers in perovskite solar cells. While graphene can provide effective protection against degradation processes\, the subsequent deposition of high-quality perovskite films onto graphene-covered surfaces presents significant difficulties due to the surface chemistry and wetting properties of graphene. \nFinally\, the seminar will address the characterization of surface electronic properties through work function measurements and inverse photoemission spectroscopy. By probing the electronic structure and energetics of graphene-based interfaces\, these techniques contribute to a deeper understanding of charge transport mechanisms\, which remain among the main challenges limiting the implementation of graphene in high-efficiency photovoltaic devices. \n  \nShort Bio/CV \nDr. Valeria del Campo is an Associate Professor in the Physics Department at Universidad Técnica Federico Santa María (Chile)\, where she currently serves as Head of the Engineering Physics Program. She coordinates the Solar Sustainable Solutions research line at the Solar Energy Research Center (SERC Chile)\, a multidisciplinary center dedicated to advance in public policies based on scientific findings. \nHer research interests focus on photovoltaic solar energy\, graphene and other advanced materials for solar cells\, and the impact of environmental factors such as dust deposition on photovoltaic performance. Her work combines surface and interface characterization with the development of materials and technologies for high-efficiency and sustainable solar energy conversion. \n_ \nContact : deborah.verger@grenoble-inp.fr \n 
URL:https://sfp-alpes.fr/event/valeria-del-campo-physics-department-universidad-tecnica-federico-santa-maria-chile/
LOCATION:LMGP – salle des séminaires\, Grenoble INP -Phelma 3 parvis Louis Néel\, Grenoble\, 38054\, France
CATEGORIES:Séminaire
ORGANIZER;CN="LMGP":MAILTO:deborah.verger@grenoble-inp.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261207T000000
DTEND;TZID=Europe/Paris:20261207T235959
DTSTAMP:20261015T140507Z
CREATED:20261015T140442Z
LAST-MODIFIED:20261015T140507Z
UID:10000307-1796601600-1796687999@sfp-alpes.fr
SUMMARY:BiGre Days
DESCRIPTION:Join us for this second edition of the BiGre Day\, a one-day conference bringing together the vibrant community of computational biology\, biostatistics\, bioinformatics\, and biophysics in Grenoble. \nWe aim to provide a platform for young (and less young) local researchers to share their work and foster collaboration. \nThe event will take place in the IMAG building’s main amphitheater. \nThe abstract submission and registration are open for this second  edition of the BIGRE day (Bionformatics in Grenoble\, December 7th)\,  using this form : https://framaforms.org/bigre-day-2026-1790948231-0 \nAbstract submission deadline : 2026-11-04 (November 4th)\nRegistration deadline : 2026-11-24 (November 24th)\nTalk or poster acceptance notifications : mi-November \nThe program will be announced here: https://bi-gre.github.io/days/ \nIt will feature :\n– A keynote talk (Clémence Frioux\, INRIA Bordeaux)\,\n– and contributed talks and posters\n– Covering all areas of bioinformatics in a broad sense (including\ncomputational biology\, biostatistics\, biomathematics\, etc) \nRegistration is free but mandatory. \n_ \nContact : antoine.frenoy@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/bigre-days/
LOCATION:IMAG – Salle de Réunion\, 150 place du Torrent\, St Martin d’Hères\, 38400\, France
CATEGORIES:Conférence,Evènements
ORGANIZER;CN="TIMC - IMAG":MAILTO:lucie.lamothe@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261207T000000
DTEND;TZID=Europe/Paris:20261210T235959
DTSTAMP:20261015T130604Z
CREATED:20260925T160459Z
LAST-MODIFIED:20261015T130604Z
UID:10000276-1796601600-1796947199@sfp-alpes.fr
SUMMARY:SFN School on TOF spectroscopy
DESCRIPTION:We are pleased to announce that pre-registation for the SFN School on TOF spectroscopy are open until October 16th.. The school will take place 7-10th of December 2026 at the Institut Laue-Langevin in Grenoble.\n\nThe objective of this school is to accompany the French neutron community towards the use of Time-of-flight spectrometers in spallation sources\, and especially in preparation for the use of the upcoming instruments suite at the ESS.  This school is addressed to participants (permanent and non-permanent) who are already familiar with neutron spectroscopy. To ensure a high pedagogical quality and interactions during tutorials and practicals\, attendance will be limited to 30 participants. Selection will be based on a short CV and brief statement of motivation. Priority will be given to participants from the French community but registration may be extended to international users depending on attendance.\n\nPlease submit your application before October 16th 2026.\n\nFull details\, including important dates\, registration information and program are available on the website: https://workshops.ill.fr/e/SFN2ESS\n\nFor any questions\, please contact us at : SFN2ESS@ill.fr
URL:https://sfp-alpes.fr/event/sfn-school-on-tof-spectroscopy/
LOCATION:ILL 50 building – room 101\, EPN Campus - 71 avenue des Martyrs\, Grenoble\, 38000\, France
CATEGORIES:Ecole,Evènements
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261208T110000
DTEND;TZID=Europe/Paris:20261210T173000
DTSTAMP:20261002T145553Z
CREATED:20260911T140120Z
LAST-MODIFIED:20261002T145553Z
UID:10000254-1796727600-1796923800@sfp-alpes.fr
SUMMARY:ECHO workshop - EleCtron Holography in Optics
DESCRIPTION:This is a kind reminder that the EleCtron Holography in Optics (ECHO) workshop will be held in Forschungszentrum Jülich from 8 to 10 December 2026. The workshop will cover topics that include electromagnetic field mapping at the nanoscale using electron and X-ray holography. It will be funded by the WE-Heraeus foundation\, who will cover the costs of registration\, accommodation and meals. The deadline for abstract submission is September 14th. \nPlease find the list of invited speakers and information about how to register at the following link : https://er-c.org/index.php/conferences-2/echo-seminar/
URL:https://sfp-alpes.fr/event/echo-workshop-electron-holography-in-optics/
CATEGORIES:Evènements,Workshop
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261209T140000
DTEND;TZID=Europe/Paris:20261209T150000
DTSTAMP:20261022T100252Z
CREATED:20261022T100252Z
LAST-MODIFIED:20261022T100252Z
UID:10000315-1796824800-1796828400@sfp-alpes.fr
SUMMARY:Soutenance de thèse par Simon PAUL (CEA-Irig/BGE)
DESCRIPTION:L’hypoxie comme composante du microenvironnement pulmonaire profibrosant : exploration des mécanismes moléculaires par des approches expérimentales multi-omiques et multi-modèles\nRésumé : \nLa fibrose pulmonaire idiopathique (FPI) est une maladie pulmonaire interstitielle progressive\, dont l’évolution est généralement fatale et dont les mécanismes d’initiation\, de progression ou d’exacerbation restent incomplètement caractérisés. Plusieurs études ont mis en évidence une hypoxie localisée au niveau de l’épithélium alvéolaire des poumons fibrosés\, particulièrement dans les cellules épithéliales alvéolaires de type 2 situées dans les territoires fibrosants. L’imagerie au [18F]FMISO a également suggéré que l’hypoxie pouvait précéder l’apparition de lésions fibrosantes. Ces observations soulèvent l’hypothèse que l’hypoxie ne constitue pas uniquement une conséquence du remodelage tissulaire\, mais pourrait également moduler les processus de fibrogenèse selon le contexte profibrosant dans lequel elle survient. L’objectif de cette thèse est d’explorer le rôle de l’hypoxie au sein du microenvironnement profibrosant selon deux axes complémentaires. Le premier vise à identifier les signatures moléculaires communes aux contextes hypoxiques et fibrosants\, puis à déterminer dans quelle mesure elles sont retrouvées dans la FPI humaine. Le second vise à évaluer l’impact de l’hypoxie sur les réponses moléculaires et tissulaires lorsqu’elle survient au sein d’un environnement profibrosant. \nLe premier axe repose sur l’intégration de données transcriptomiques issues de différents modèles murins d’hypoxie et de fibrose\, complétée par des analyses protéomiques in vivo et la comparaison avec des données transcriptomiques humaines de FPI. Cette approche a permis d’identifier une signature moléculaire commune aux contextes hypoxiques et fibrosants\, dont une composante est retrouvée dans la FPI humaine. Elle a également conduit à prioriser plusieurs candidats moléculaires pour approfondir l’étude des mécanismes reliant hypoxie et fibrogenèse. \nLe second axe s’appuie sur un modèle ex vivo de tranches pulmonaires murines (precision-cut lung slices\, PCLS)\, complété par un modèle in vitro de cellules épithéliales alvéolaires humaines dérivées de cellules souches pluripotentes induites (iAT2). Les analyses protéomiques montrent que l’ajout d’hypoxie modifie la réponse au stimulus profibrosant\, avec des effets dépendant de la nature de ce stimulus. Dans les deux modèles\, l’association du cocktail fibrosant et de l’hypoxie s’accompagne d’un enrichissement de la voie de la transition épitélio-mésenchymateuse et d’une convergence avec certaines signatures moléculaires de la FPI. La comparaison des deux modèles a également permis d’identifier un candidat moléculaire commun\, ouvrant une piste pour étudier les mécanismes reliant l’hypoxie au remodelage de la matrice extracellulaire. Dans leur ensemble\, ces travaux soutiennent l’hypothèse selon laquelle l’hypoxie constitue une composante biologiquement active du microenvironnement profibrosant\, susceptible de moduler les réponses moléculaires associées à la fibrogenèse. Ils ouvrent de nouvelles perspectives pour la caractérisation les mécanismes reliant hypoxie\, réponse épithéliale et remodelage de la matrice extracellulaire. \n_ \nContact : irig.communication@cea.fr
URL:https://sfp-alpes.fr/event/soutenance-de-these-par-simon-paul-cea-irig-bge/
LOCATION:Amphithéâtre central – bâtiment Jean Roget\, Site santé\, La Tronche\, 38700\, France
CATEGORIES:Soutenance,Soutenance de Thèse
ORGANIZER;CN="IRIG - CEA":MAILTO:irig.communication@cea.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261211T000000
DTEND;TZID=Europe/Paris:20261212T235959
DTSTAMP:20261023T151109Z
CREATED:20261023T151109Z
LAST-MODIFIED:20261023T151109Z
UID:10000325-1796947200-1797119999@sfp-alpes.fr
SUMMARY:Pièce de Theâtre Supraconducteur
DESCRIPTION:La SFP Alpes co-organise la venue du Spectacle Supraconducteur co-écrit et co-joué par notre collègue du CEA Hugues Pothier\, et nos nouveaux lauréats du Prix Jean Perrin le Groupe N+1 : plusieurs représentation entre le Vendredi 11 et Samedi 12 Décembre (save ze date !)
URL:https://sfp-alpes.fr/event/piece-de-theatre-supraconducteur/
CATEGORIES:Evènements
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261214T090000
DTEND;TZID=Europe/Paris:20261218T160000
DTSTAMP:20261002T143158Z
CREATED:20261002T142004Z
LAST-MODIFIED:20261002T143158Z
UID:10000293-1797238800-1797609600@sfp-alpes.fr
SUMMARY:School on Neutron Diffraction Data Treatment using the FullProf Suite
DESCRIPTION:We are delighted to announce the 2026 School on Neutron Diffraction Data Treatment using the FullProf Suite\, which will take place at the Institut Laue-Langevin (ILL) in Grenoble\, France\, from 14 to 18 December 2026. \nThis Edition will place a special emphasis on the analysis of magnetic structures\, alongside the treatment of both X-ray and neutron diffraction data. The school is designed to provide in-depth\, hands-on training using the FullProf Suite\, with a balance of tutorials and lectures delivered by experts in the field. \n🔗 Further details and application: \nVisit our website at: https://workshops.ill.fr/e/FullProfSchool2026 \nRegistration is open and we warmly encourage you to register for this School. \n🎯 Scientific Scope \nThe 2026 FullProf School aims to train scientists in the effective treatment of X-ray and neutron diffraction data\, with a particular focus on magnetic structure determination and the latest features in materials science data analysis. \nParticipants will benefit from intensive practical sessions\, making extensive use of the FullProf Suite\, complemented by targeted lectures that cover the theoretical background necessary for intermediate-level users. \n🎯 Lectures & Tools \nThis session will highlight the use of FullProf Suite in combination with external tools such as the Bilbao Crystallographic Server and ISODISTORT\, especially for applications related to magnetic structures. \n👥 Who Should Apply? \nThe school is intended for PhD students and experienced researchers with a solid background in powder diffraction and/or single crystal crystallography. To ensure personalized support and effective interaction\, the number of participants is limited to 30. \nPlaces will be allocated on a first-come\, first-served basis\, and registration will only be confirmed upon receipt of payment. Once capacity has been reached\, additional applicants will be placed on a waiting list. \nWe would appreciate it if you could forward this announcement to colleagues or students who may be interested. \nWe apologize if you receive this message more than once\, and look forward to welcoming you in Grenoble! \n_ \nContact : FPSschool@ill.fr
URL:https://sfp-alpes.fr/event/school-on-neutron-diffraction-data-treatment-using-the-fullprof-suite/
LOCATION:ILL 50 building – room 110\, EPN Campus - 71 avenue des Martyrs\, Grenoble\, 38000\, France
CATEGORIES:Ecole,Evènements
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261216T123000
DTEND;TZID=Europe/Paris:20261216T133000
DTSTAMP:20260723T165459Z
CREATED:20260723T165117Z
LAST-MODIFIED:20260723T165459Z
UID:10000220-1797424200-1797427800@sfp-alpes.fr
SUMMARY:Roland LEHOUCQ
DESCRIPTION:Science-fiction : le monde de la (dé)mesure\n_ \nToutes les informations sont disponibles sur : https://indico.ijclab.in2p3.fr/event/13626/ \nContact : louis.fayard@IJCLAB.INP3.FR
URL:https://sfp-alpes.fr/event/roland-lehoucq/
LOCATION:Université Paris-Saclay – Bâtiment 625 (Hbar) – Amphi A1\, Rue Joliot Curie\, Orsay\, 91400\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261218T090000
DTEND;TZID=Europe/Paris:20261218T110000
DTSTAMP:20261002T135937Z
CREATED:20261002T135937Z
LAST-MODIFIED:20261002T135937Z
UID:10000292-1797584400-1797591600@sfp-alpes.fr
SUMMARY:Soutenance de thèse par Francesca MOSCA (CEA-Irig/IBS)
DESCRIPTION:Targeting L\,D-Transpeptidases in Lpp-Peptidoglycan Crosslinking in E.coli\nRésumé : \nThis thesis investigated the structure and function of L\,D-transpeptidases (LDTs) responsible for covalently attaching Braun’s lipoprotein (Lpp) to the peptidoglycan layer in Gram-negative bacteria. Because Lpp constitutes the principal covalent connection between the peptidoglycan and the outer membrane\, disruption of this linkage destabilises the bacterial cell envelope. Understanding the molecular mechanisms underlying LDT-mediated Lpp attachment therefore provides a foundation for developing novel inhibitors capable of compromising outer-membrane integrity and enhancing the activity of existing antibiotics against antibiotic-resistant Gram-negative bacteria. The work focused on mainly two aspects of LDT function : the interactions of these enzymes with existing and novel antibiotics\, and with their physiological substrates Lpp and peptidoglycan. Particular emphasis was placed on LdtB\, the most essential LDT in E. coli. Structural and functional characterization was performed using NMR spectroscopy\, biophysical methods\, and biochemical techniques\, complemented by in silico approaches\, including molecular dynamics simulations.This integrative approach was used to decipher the molecular determinants of Lpp-peptidoglycan transpeptidation mechanism and to propose a possible stuctural model for the reaction\, which remains poorly understood despite its biological relevance. In this context\, E. coli served as a model system\, whose study may provide insights into mechanisms that could be conserved across other Gram-negative bacteria. This work was carried out within the framework of the BREAKthrough consortium\, which enabled part of the research to be conducted in collaboration with partner laboratories across Europe​. ​​​​ \n_ \n\n\n​Les séminaires et soutenances sont ouverts à tous\, notez toutefois que l’accès au campus EPN nécessite un avis de rendez-vous. Merci de remplir ce formulaire  et de l’adresser\, plus de 48h à l’avance\, à ce contact. \n\n\n\n\nPensez à vous munir d’une pièce d’identité le jour de votre visite.
URL:https://sfp-alpes.fr/event/soutenance-de-these-par-francesca-mosca-cea-irig-ibs/
LOCATION:IBS – Salle des séminaires\, IBS 71 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Soutenance,Soutenance de Thèse
ORGANIZER;CN="IBS":MAILTO:ibs.seminaires@ibs.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20270114T160000
DTEND;TZID=Europe/Paris:20270114T170000
DTSTAMP:20260723T165928Z
CREATED:20260723T165928Z
LAST-MODIFIED:20260723T165928Z
UID:10000221-1799942400-1799946000@sfp-alpes.fr
SUMMARY:Emilia ROBIN
DESCRIPTION:Comment on a construit Orsay\n_ \nToutes les informations sont disponibles sur : https://indico.ijclab.in2p3.fr/event/13925/ \nContact : louis.fayard@IJCLAB.INP3.FR
URL:https://sfp-alpes.fr/event/emilia-robin/
LOCATION:Laboratoire IJCLab – Auditorium Pierre Lehmann\, Rue Ampère\, Orsay cedex\, 91898\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20270627T000000
DTEND;TZID=Europe/Paris:20270701T235959
DTSTAMP:20261015T133306Z
CREATED:20260227T160121Z
LAST-MODIFIED:20261015T133306Z
UID:10000090-1814054400-1814486399@sfp-alpes.fr
SUMMARY:European Conference on Neutron Scattering
DESCRIPTION:We are delighted to announce that abstract submission for ECNS 2027 is now open.\n\nhttps://www.ecns2027.eu/program/ \nThe European Conference on Neutron Scattering will take place from June 28 to July 1\, 2027\, at the Université Grenoble Alpes in the heart of the French Alps. The ECNS typically brings together more than 600 participants from across Europe and beyond. \nWe warmly invite you to contribute to the scientific programme by submitting your latest results\, ideas and perspectives. Whether you are working on applications of neutron techniques or exploring new scientific directions\, we look forward to sharing and discussing your work with the community. \nBeyond the scientific programme\, ECNS 2027 will offer plenty of opportunities to meet colleagues\, exchange ideas and discover Grenoble and its unique scientific and Alpine environment \nWe look forward to receiving your abstracts and welcoming you to Grenoble in 2027 !  \n_ \nContact : ecns2027_contact@ill.eu
URL:https://sfp-alpes.fr/event/european-conference-on-neutron-scattering/
LOCATION:Université Grenoble Alpes (UGA)\, 621 avenue Centrale\, Saint-Martin-d'Hères\, 38400\, France
CATEGORIES:Conférence,Evènements
END:VEVENT
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