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TZID:Europe/Paris
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260707T110000
DTEND;TZID=Europe/Paris:20260707T120000
DTSTAMP:20260702T132320Z
CREATED:20260702T132320Z
LAST-MODIFIED:20260702T132320Z
UID:10000213-1783422000-1783425600@sfp-alpes.fr
SUMMARY:Jérémie TOPIN (Department of Chemistry\, Université Côte d'Azur\, Nice)
DESCRIPTION:The molecular language of smell : reading odors through receptors\nRésumé : \nThis morning\, you may have enjoyed a cup of coffee or tea and felt that its aroma had stimulated your sense of smell. The volatile molecules in your favourite beverage are recognized by the olfactory receptors (ORs) expressed in your olfactory epithelium. But among your 400 ORs\, which ones were activated by these molecules ?\nTo answer this question\, and more generally to determine the molecular recognition spectrum of ORs\, we design the Molecule to Olfactory Receptor M2OR database\n(https://m2or.chemsensim.fr/)\, which brings together 75\,050 bioassay experiments for 51\,683 distinct OR-molecule pairs.[1] We further combine protein language[2] with graph neural networks to predict OR activation\, and propose a tailored architecture incorporating inductive biases from the protein-molecule interaction.[3] This model outperforms state-of-the-art drug- target interaction prediction models as well as standard GNN baselines. Notably\, our predictions are in agreement with combinatorial coding theory in olfaction. \nReferences\n[1] Lalis\, M.\, Hladiš\, M.\, Khalil\, S. A.\, Briand\, L.\, Fiorucci\, S.\, & Topin\, J\, 2024. M2OR: a database of olfactory receptor–odorant pairs for understanding the molecular mechanisms of olfaction. Nucleic Acids Research\, 52(D1)\, D1370-D1379.\n[2] Elnaggar\, A.\, Heinzinger\, M.\, Dallago\, C.\, Rehawi\, G.\, Wang\, Y.\, Jones\, L.\, … & Rost\, B. (2021). Prottrans: Toward understanding the language of life through self-supervised learning. IEEE transactions on pattern analysis and machine intelligence 2022\, 44(10)\, 7112-7127.\n[3] Hladiš\, M.\, Lalis\, M.\, Fiorucci\, S.\, & Topin\, J. Matching receptor to odorant with protein language and graph neural networks 2023. In The Eleventh International Conference on Learning Representations. \nContact : lucie.sancey@univ-grenoble-alpes.fr ou emmanuel.brun@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/jeremie-topin-department-of-chemistry-universite-cote-dazur-nice/
LOCATION:IAB – Salle de séminaire\, IAB Site Santé - Allée des Alpes\, La Tronche\, 38700\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IAB":MAILTO:appaixfl@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260707T140000
DTEND;TZID=Europe/Paris:20260707T150000
DTSTAMP:20260702T133156Z
CREATED:20260702T133156Z
LAST-MODIFIED:20260702T133156Z
UID:10000214-1783432800-1783436400@sfp-alpes.fr
SUMMARY:Axel ROUVILLER (Post-doctorant)
DESCRIPTION:Electromecanical characterization of Cu2O nanowire networks\nRésumé : \nOne of the main obstacles to the development of new electronic devices\, such as photovoltaic panels\, LEDs\, smart windows\, is the lack of p-type semiconductors combining both high electrical conductivity values and transparence in the visible range. Studies carried out at the LMGP laboratory have demonstrated the possibility of forming\, by aerosol-assisted chemical vapor deposition (AACVD)\, Cu2O/CuCrO2 nanocomposites in which Cu2O nanograins are contained in a CuCrO2 matrix. These p-type semiconductor nanostructures turned out to have promising optoelectronic properties\, with an average visible transmittance of 55% and an electrical resistivity of 0.05 Ω.cm [1]. The NANOCOMPOSITE project\, supported by the ANR\, aims to develop the elaboration of this type of nanostructure in a controlled manner\, by covering Cu2O nanowire networks\, synthesized by hydrothermal process\, with a thin layer of CuCrO2\, deposited by AACVD. The work in this presentation is part of this project and concerns the development by Felhing reaction method of Cu2O nanowire networks of different densities on silicon substrates. Once these networks were characterized\, they were deposited on flexible kapton substrates\, which allowed for electrical measurements to be carried out under mechanical stress\, using a traction plate at the SIMaP laboratory. \nShort Bio/CV \nI completed my thesis at the university of Caen (France) in the CIMAP laboratory. During my PhD\, I worked on the growth and characterization of both SrVO3 and Sr2V2O7 thin films\, using reactive sputtering deposition technique\, for opto-electronics applications. Since February 2026\, I joined the NANOCOMPOSITE ANR project\, coordinated by Jean-Luc Deschanvres\, as a Post-Doc. My work on this project consists\, firstly\, in the elaboration of Cu2O nanowire networks on flexible substrates by hydrothermal growth process at LMGP laboratory. Once these depositions have been performed\, I carry out electromecanical characterizations of these nanowires at SIMaP laboratory in order to evaluate their compatibility and adequateness as flexible P-type semiconductors. \nContact : deborah.verger@grenoble-inp.fr
URL:https://sfp-alpes.fr/event/axel-rouviller-post-doctorant/
LOCATION:LMGP – salle des séminaires\, Grenoble INP -Phelma 3 parvis Louis Néel\, Grenoble\, 38054\, France
CATEGORIES:Séminaire
ORGANIZER;CN="LMGP":MAILTO:deborah.verger@grenoble-inp.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260710T110000
DTEND;TZID=Europe/Paris:20260710T120000
DTSTAMP:20260703T084646Z
CREATED:20260626T134823Z
LAST-MODIFIED:20260703T084646Z
UID:10000211-1783681200-1783684800@sfp-alpes.fr
SUMMARY:Marion JESPERSEN (Department of Microbiology\, Monash University)
DESCRIPTION:Functional and structural insights into O2-adapted hydrogenases\nRésumé : \nHydrogenases are metalloenzymes that catalyse the interconversion of protons and electrons into molecular hydrogen (H2)\, providing valuable models for robust and sustainable H2 catalysts. However\, most characterised hydrogenases are inhibited by oxygen (O2)\, limiting their biotechnological potential. Although diverse [NiFe]- and [FeFe]-hydrogenases have evolved adaptations that support activity\, stability\, or recovery following O2 exposure\, the molecular basis of O2 adaptation remains poorly understood. \nIn this talk\, I will present our ongoing work on O2-adapted hydrogenases from bacteria and archaea inhabiting aerobic soils\, thermoacidophilic environments\, and the gut. By combining physiological\, biochemical\, structural\, and computational approaches\, we investigate how distinct hydrogenase lineages support H2 metabolism under oxygen-exposed conditions.These systems include the high-affinity group 1h [NiFe]-hydrogenase from Mycobacterium smegmatis\, the Sulfolobales clade 2 [NiFe]-hydrogenase from Metallosphaera sedula\, and gut microbial [FeFe]-hydrogenases\, including group B enzymes from Bacteroides species and a group A1 enzyme from Clostridium perfringens. Together\, they highlight the diversity of hydrogenase architectures\, cofactor arrangements\, and electron-transfer strategies that may contribute to O2 resilience. \nOverall\, this work expands the functional and structural repertoire of O2-adapted hydrogenases\, informing our understanding of microbial H2 metabolism and the search for enzymes suited to H2-based biocatalysis. \n_ \nCes séminaires\, ainsi que les soutenances et cours sont ouverts à tous\, notez toutefois que l’accès au campus EPN nécessite un avis de rendez-vous. Merci de remplir ce formulaire et de l’adresser\, plus de 48h à l’avance\, à ce contact. Pensez à vous munir d’une pièce d’identité le jour de votre visite.
URL:https://sfp-alpes.fr/event/marion-jespersen-department-of-microbiology-monash-university/
LOCATION:IBS – Salle des séminaires\, IBS 71 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IBS":MAILTO:ibs.seminaires@ibs.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260720T110000
DTEND;TZID=Europe/Paris:20260720T120000
DTSTAMP:20260703T133346Z
CREATED:20260703T133346Z
LAST-MODIFIED:20260703T133346Z
UID:10000216-1784545200-1784548800@sfp-alpes.fr
SUMMARY:Garry S. HANAN (Département de chimie\, Université de Montréal\, Canada)
DESCRIPTION:Developing New Photosensitizers based on Transition Metal Ions for Green Energy Applications\nRésumé : \nRising global population and increased CO2 levels in the atmosphere have focused attention on developing alternative and widely available carbon-free energy sources (1\,2). Ourresear ch focuses on harnessing the unique properties of excited states in metal complexes to drive self-assembly processes and develop innovative energy applications. By leveraging the photophysical and photochemical behaviors of these complexes\, we explore how light-induced excitations can be utilized to control molecular organization and energy transfer at the nanoscale. The parallels with Natural Photosynthesis are evident: light energy is captured by self-assembled Light Harvesting Complexes and is channeled to a reaction centre which induces electron transfer and the eventual production of chemical energy (3). \nOur approach involves the synthesis of polypyridyl-based metal complexes\, which are known for their stability and tunable electronic properties. By manipulating the excited states of these complexes\, we demonstrate how light can act as a stimulus to induce self-assembly\, leading to the formation of well-defined nanostructures with potential applications in catalysis\, sensing\, and optoelectronics (4). Additionally\, we extend our approach to the development of photoactive molecular devices capable of storing and transferring electrons\, offering insights into the design of next-generation photosensitizers for chemical energy production (5). We have also moved from second- and third-row transition metal ions to the first row\, and explore energy applications of these abundant\, inexpensive and relatively non-toxic metal ions (6). \nReferences\n1. https://ourworldindata.org/world-population-growth (01-05-2026).\n2. https://www.iea.org/world (01-05-2026).\n3. V. Balzani\, A. Credi\, M. Venturi\, Chem Sus Chem 2008\, 1\, 26.\n4. B. Laramée-Milette\, F. Puntoriero\, F. Nastasi\, S. Campagna\, G. S. Hanan\, Chem. Eur. J.\, 2017 23\, 16497.\n5. G. M. Mercier\, E. Rousset\, I. Oubaha\, K. Bandyopadhyay\, A. K. Pal\, I. Ciofini\, L.-M. Chamoreau\, V. Marvaud\, G. S. Hanan\, Chem. Commun. 2025 61 (77)\, 14911-14914.\n6. A. Saha\, G. Turner\, M. Cibian\, S. Serroni\, S. Genovese\, S. Campagna\, G. S. Hanan\, F. Nastasi\, submitted for publication. \nGarry Hanan is professor in the Department of Chemistry at the Université de Montréal\, where he leads the Green Energy Group and is a member of the Centre for Green Chemistry and Catalysis. He earned his B. Sc. from the University of Winnipeg\, Canada\, his PhD from Université Louis Pasteur in Strasbourg\, France\, under the supervision of Jean-Marie Lehn and subsequently conducted postdoctoral studies in Germany with Manfred T. Reetz and in Italy with Vincenzo Balzani and Sebastiano Campagna. Professor Hanan’s research focuses on the design and synthesis of supramolecular photocatalysts capable of harvesting solar energy to drive chemical\ntransformations\, most notably the photoproduction of fuels via water-splitting (producing H₂) and CO₂ reduction.\nHe has received numerous distinctions\, including awards from IUPAC and NSERC\, highlighting his contributions to sustainable chemistry and molecular materials science. He also actively promotes international student exchange. \nContact : frederique.loiseau@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/garry-s-hanan-departement-de-chimie-universite-de-montreal-canada/
LOCATION:DCM – Salle C209\, DCM - Bât Chimie Recherche 301 rue de la Chimie\, St Martin d'Hères\, 38400\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260721T140000
DTEND;TZID=Europe/Paris:20260721T150000
DTSTAMP:20260709T121303Z
CREATED:20260709T121303Z
LAST-MODIFIED:20260709T121303Z
UID:10000218-1784642400-1784646000@sfp-alpes.fr
SUMMARY:Ben HUMPHREYS (Institut Laue-Langevin (ILL) Grenoble\, France)
DESCRIPTION:Advancing our Understanding of Responsive Polymer Brushes\nRésumé : \n\nInterfacial properties of a surface can be extensively modified through the addition of a polymer brush layer; a dense array of end-tethered polymers grafted to a surface. When a polymer brush is synthesised with a stimulus responsive polymer\, the surface properties can be tailored to respond\, often reversibly\, to external stimuli such as temperature\, light\, pH\, solvent or electric fields. While these so-called smart materials are particularly promising for high-value applications such as sensors\, nanoactuation and microfluidics\, their response can be significantly influenced by additives such as osmolytes and salts. Unlike untethered polymer systems\, research into the influence of additives for responsive polymer brushes has been sparse\, yet this knowledge is crucial when advancing their utilisation in biomedical and industrial applications. \nThroughout my research career I have primarily focused on the influence of salts and osmolytes on temperature and pH responsive homo- and co-polymer brushes. I will firstly discuss my synthetic methodologies and choice of responsive polymers. This will be followed by a comprehensive outline of the approaches used to investigate these responsive coatings. Here\, starting with the simplest systems\, then gradually increasing complexity\, I have been able to systematically understand the influence of individual additives/changes. This information is invaluable when considering the complex real-world applications that can benefit from the utilisation of smart\, responsive polymer brush surface coatings. \nShort Bio/CV\nIn 2015 I graduated from the University of Newcastle\, Australia\, with a Bachelor of Science\, 1st class honors\, majoring in Chemistry\, followed by my PhD at the same university (2015-2019) titled “Nanostructure of Temperature Responsive Polymer Brushes Modulated by Salt Identity”. I then accepted a post-doc position at Lund University in Sweden\, investigating the internal structural changes of a triglyceride film throughout enzymatic digestion\, with particular focus on the influence of pH and how this influences the species present throughout the lipolytic process. In 2023 I started in my current position as instrument responsible for the D17 neutron reflectometer at the ILL where I have re-established my research on responsive polymer brushes with a focus on osmolyte and salt additives in aqueous solutions. \n_ \nContact : deborah.verger@grenoble-inp.fr
URL:https://sfp-alpes.fr/event/ben-humphreys-institut-laue-langevin-ill-grenoble-france/
LOCATION:LMGP – salle des séminaires\, Grenoble INP -Phelma 3 parvis Louis Néel\, Grenoble\, 38054\, France
CATEGORIES:Séminaire
ORGANIZER;CN="LMGP":MAILTO:deborah.verger@grenoble-inp.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260831T140000
DTEND;TZID=Europe/Paris:20260831T150000
DTSTAMP:20260709T120641Z
CREATED:20260709T120641Z
LAST-MODIFIED:20260709T120641Z
UID:10000217-1788184800-1788188400@sfp-alpes.fr
SUMMARY:Sasha CHERNYSHEV (University of California\, Irvine\, USA)
DESCRIPTION:BaCo₂(AsO₄)₂ : Strong Kitaev\, After All\nRésumé : \nBaCo₂(AsO₄)₂ – a magnetic compound first studied some 50 years ago—has long been a mystery. Its spectrum is incompatible with the theory that this material was supposed to verify\, and its magnetic order is discrepant and easily destroyed by an exceptionally low magnetic field. All these traits have perplexed theorists and experimentalists alike. The mystery had to wait for breakthroughs such as the development of the novel concept of « Kitaev magnetism » in the late 2000s. It had to wait even longer as the first\, more obvious Kitaev candidates were studied\, before researchers turned their attention to the cobaltate family. Only recently did the stars align to enable a comprehensive analysis of this enduring enigma. Our work [1] has provided exactly that: it propelled BaCo₂(AsO₄)₂ to the forefront of research as a champion among Kitaev magnets\, while bringing its multifaceted conundrums close to a complete resolution by reconciling its puzzling magnetic state\, spectrum\, and low critical field with the phenomenology of the proposed model. \n[1] P. A. Maksimov\, S. Jiang\, L. P. Regnault\, and A. L. Chernyshev\, Phys. Rev. Lett. 135\, 066703 (2025). (Editors’ Suggestion). \n_ \nArno Hiess (College 4 Secretary) \nExternal visitors may ask for a site access to tellier(at)ill.fr \nZoom link : https://ill.zoom.us/j/94822992547?pwd=STd44Z3otZU5k1DXbwobbeLtQPJJq2.1 – Password : SeminarC4
URL:https://sfp-alpes.fr/event/sasha-chernyshev-university-of-california-irvine-usa/
LOCATION:ILL – Salle de Séminaire (110-111)\, ILL 50 71 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260901T140000
DTEND;TZID=Europe/Paris:20260901T150000
DTSTAMP:20260827T151536Z
CREATED:20260827T151536Z
LAST-MODIFIED:20260827T151536Z
UID:10000223-1788271200-1788274800@sfp-alpes.fr
SUMMARY:Tomáš NOVOTNY (Charles University\, Praha\, Czech Republic)
DESCRIPTION:Theoretical approaches to correlated quantum dots coupled to superconducting leads\nRésumé : \nI will present a brief overview of relatively simple theoretical approaches developed in our Prague group in past several years and applied to the problem of description of correlated quantum dots attached to the BCS superconducting leads. As a thorough Quantum Monte Carlo analysis (1) of the experimental data (2) showed realistic experimental setups can be even quantitatively captured by the Single Impurity Anderson Model (SIAM) with superconducting leads. Pioneering semi-analytical approaches have not matched the so far employed heavy numerical tools such as Numerical Renormalization Group (NRG) and/or Quantum Monte Carlo (QMC) in the ability of quantitatively predicting the properties of this model. However\, we have shown that self-consistent perturbation expansion up to the second order in the interaction strength (3) yields at zero temperature and for a wide range of other parameters excellent results for the position of the 0 − π impurity quantum phase transition boundary and the Josephson current as well as the energy of Andreev bound states in the 0-phase. Furthermore\, we have discovered exact identities connecting symmetric and asymmetric coupling situations which significantly reduce computational requirements in experimentally generic asymmetric setups (4) and provided simple approximate analytical formulas for the fitting of the phase boundaries from finite-temperature experimental data (5). I will also briefly mention an exact mapping of a half-filled superconducting SIAM onto a normal SIAM with a structured semiconducting lead which simplifies some technical aspects of its NRG solution significantly (6) and a simple way of determination of the quantum critical point from finite-temperature QMC statistics (7). Finally\, the most recent extensions of those methods to more quantum dots (8) or superconducting leads (9) will be mentioned. \n(1) David J. Luitz\, Fakher F. Assaad\, Tomáš Novotný\, Christoph Karrasch\, and Volker Meden\, Understanding the Josephson current through a Kondo-correlated quantum dot\, Phys. Rev. Lett. 108\, 227001 (2012).\n(2) H. Ingerslev Jørgensen\, T. Novotný\, K. Grove-Rasmussen\, K. Flensberg\, and P. E. Lindelof\, Critical Current 0-π Transition in Designed Josephson Quantum Dot Junctions\, Nano Lett. 7 (8)\, 2441 (2007).\n(3) M. Žonda\, V. Pokorný\, V. Janiš\, and T. Novotný\, Perturbation theory of a superconducting 0-π impurity quantum phase transition\, Scientific Reports 5\, 8821(2015); Perturbation theory for an Anderson quantum dot asymmetrically attached to two superconducting leads\, Phys. Rev. B 93\, 024523 (2016).\n(4) Alžběta Kadlecová\, Martin Žonda\, and Tomáš Novotný\, Quantum dot attached to superconducting leads: Relation between symmetric and asymmetric coupling\, Phys. Rev. B 95\, 195114 (2017).\n(5) Alžběta Kadlecová\, Martin Žonda\, Vladislav Pokorný\, and Tomáš Novotný\, Practical Guide to Quantum Phase Transitions in Quantum-Dot-Based Tunable Josephson Junctions\, Phys. Rev. Applied 11\, 044094 (2019).\n(6) Peter Zalom\, Vladislav Pokorný\, and Tomáš Novotný\, Spectral and transport properties of a half-filled Anderson impurity coupled to phase-biased superconducting and metallic leads\, Phys. Rev. B 103\, 035419 (2021); Peter Zalom and Tomáš Novotný\, Tunable reentrant Kondo effect in quantum dots coupled to metal-superconducting hybrid reservoirs\, Phys. Rev. B 104\, 035437 (2021).\n(7) V. Pokorný and T. Novotný\, Footprints of impurity quantum phase transitions in quantum Monte Carlo statistics\, Phys. Rev. Research 3\, 023013 (2021).\n(8) M. Žonda\, P. Zalom\, T. Novotný\, G. Loukeris\, J. Bätge\, and V. Pokorný\, Generalized atomic limit of a double quantum dot coupled to superconducting leads\, Phys. Rev. B 107\, 115407 (2023).\n(9) Peter Zalom\, Martin Žonda\, and Tomáš Novotný\, Hidden Symmetry in Interacting-Quantum-Dot-Based Multiterminal Josephson junctions\, Phys. Rev. Lett. 132\, 126505 (2024). \n_ \nContact : equipe-seminaires-nano@listes.grenoble.cnrs.fr
URL:https://sfp-alpes.fr/event/tomas-novotny-charles-university-praha-czech-republic/
LOCATION:CNRS – Salle Rémy Lemaire (K223)\, CNRS - Institut Néel 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260904T110000
DTEND;TZID=Europe/Paris:20260904T120000
DTSTAMP:20260828T125150Z
CREATED:20260828T125150Z
LAST-MODIFIED:20260828T125150Z
UID:10000232-1788519600-1788523200@sfp-alpes.fr
SUMMARY:Sara MATYAS​ (Ingénieur innovation)​ & Stéphanie CELIS-JUAREZ (CNRS\, Direction des Relations Territoriales\, DR11)
DESCRIPTION:La Valorisation : quels dispositifs d’accompagnement au CNRS ?\nRésumé : \nLors de ce séminaire\, les dispositifs d’accompagnement en valorisation proposés par le CNRS vous seront présentés. Une opportunité de mieux connaitre les guichets de financement mais aussi de reparler de la déclaration d’invention\, point de départ de toute démarche de valorisation. \nLes guichets Prématuration CNRS et PUI\, Programme PISE\, Programme RISE vous seront notamment présentés\, ainsi que des Programmes de financement 2027 ciblant des projets à impacts sociétaux et environnementaux. \nEnfin\, un temps d’échange avec les oratrices permettra de répondre aux questions relatives à vos projets. \n_ \n\nLes séminaires et soutenances sont ouverts à tous\, notez toutefois que l’accès au campus EPN nécessite un avis de rendez-vous. Merci de remplir ce formulaire  et de l’adresser\, plus de 48h à l’avance\, à ce contact.\nPensez à vous munir d’une pièce d’identité le jour de votre visite.
URL:https://sfp-alpes.fr/event/sara-matyas-ingenieur-innovation-stephanie-celis-juarez-cnrs-direction-des-relations-territoriales-dr11/
LOCATION:IBS – Salle des séminaires\, IBS 71 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IBS":MAILTO:ibs.seminaires@ibs.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260908T110000
DTEND;TZID=Europe/Paris:20260908T120000
DTSTAMP:20260903T153516Z
CREATED:20260903T153408Z
LAST-MODIFIED:20260903T153516Z
UID:10000238-1788865200-1788868800@sfp-alpes.fr
SUMMARY:Delphine DELACOUR (IBDM \, Marseille (France))
DESCRIPTION:Deciphering the principles of epithelial tissue organization\nRésumé : \nEpithelia constitute the primary physical barrier against external insults while simultaneously ensuring organ function. Defects in epithelial assembly or function lead to a broad spectrum of pathological conditions\, ranging from rare developmental disorders to cancer. Despite their fundamental importance\, the mechanisms by which epithelial cells coordinate individual behaviors across entire tissues to ensure spatial organization\, integrity\, and function remain poorly understood. To date\, epithelial coherence has been studied predominantly in invertebrate systems or in transformed cell lines\, limiting our understanding of its regulation in physiological mammalian contexts.\nThe intestinal epithelium represents an exceptional model to address these questions. It is one of the most rapidly renewing tissues in mammals and is continuously exposed to challenges. Its homeostasis relies on the precise balance between cell proliferation\, differentiation\, migration\, and death. However\, the cellular and developmental principles governing intestinal tissue organization and maintenance remain largely unexplored. \nThe overarching objective of this project is to elucidate how functional domains of the intestinal epithelium are established\, maintained\, and coordinated in space and time. Specifically\, the project aims to : \n1. understand the mechanisms that preserve the integrity of the proliferative compartment and determine their role in crypt formation and maintenance ;\n2. uncover epithelial connectivity and collective behavior within the differentiated compartment\, both under homeostatic conditions and in response to perturbations. \nA major strength of this project lies in its integrative and comparative strategy\, combining in vivo and in vitro murine models with human disease-relevant systems. The project brings together advanced approaches in cell and developmental biology\, tissue engineering\, histology\, molecular biology\, biophysics\, and computational modeling. This multidisciplinary framework will enable the identification of adaptive mechanisms by which epithelial cells polarize\, self-organize\, and dynamically regulate their fate in response to their environment\, with broad implications for developmental biology\, regenerative medicine\, and disease pathology. \n_ \nContact : monika.dolega@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/delphine-delacour-ibdm-marseille-france/
LOCATION:IAB – Salle de séminaire\, IAB Site Santé - Allée des Alpes\, La Tronche\, 38700\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IAB":MAILTO:appaixfl@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260908T140000
DTEND;TZID=Europe/Paris:20260908T150000
DTSTAMP:20260827T152108Z
CREATED:20260827T152108Z
LAST-MODIFIED:20260827T152108Z
UID:10000224-1788876000-1788879600@sfp-alpes.fr
SUMMARY:Paul CANFIELD (Ames Laboratory\, Iowa State University\, Ames\, Iowa 50010\, USA)
DESCRIPTION:Negotiations with Nature — What happens when a Physicist tries to be a Chemist\nRésumé : \nOver the past 30 plus years my group has made over 10\,000 solution growth attempts to grow or explore 1\,000’s of different compounds or phase spaces. Over the past decade we have been developing a variety of different algorithms for identifying and accessing poorly explored spaces\, partly with an eye toward discovering new phases\, partly with an eye toward discovering new electrical or magnetic phase transitions and ground states. In this talk I will try to address the basic research questions of\, “where should I look for new materials or physics?” and “how can I enhance my chances of discovering X\, Y\, or Z (where XYZ can be your favorite state\, structure or behavior)?”. Specific examples spanning superconductors\, quasicrystals\, heavy fermions\, fragile magnets\, topological electronic systems\, local moment magnets and a few lost puppies will be given and reviewed. \n_ \nContact : jean-pascal.brison@cea.fr
URL:https://sfp-alpes.fr/event/paul-canfield-ames-laboratory-iowa-state-university-ames-iowa-50010-usa/
LOCATION:GreenER – Amphi Bergès\, GreenER\, 21 avenue des Martyrs\, Grenoble\, 38031\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260910T143000
DTEND;TZID=Europe/Paris:20260910T153000
DTSTAMP:20260904T141514Z
CREATED:20260904T141514Z
LAST-MODIFIED:20260904T141514Z
UID:10000240-1789050600-1789054200@sfp-alpes.fr
SUMMARY:Kayla NGUYEN (Oregon University)
DESCRIPTION:Three-Dimensional Atomic Reconstruction using Electron Ptychography\nRésumé : \nElectrons play a pivotal role in stabilizing matter\, but they are also tools that can reveal the underlying physics of complex systems from high energy physics to condensed matter. Electrons can be used as imaging probes\, where properties of matter such as magnetism or topology can be observed atom-by-atom.  In this talk\, I will show how electron ptychography\, a computational phase retrieval technique\, can improve resolution beyond the numerical aperture of electromagnetic lenses and reveal atomic structures in three-dimensions.  In particular\, I use this ‘computation lens’ approach on Er: CeO2 nanocrystals and thin films with dramatically different crystallographic orientations to uncover dopants\, defects and strain with picometer precision.  Ptychography can also be extended to visualize topological magnetism in three dimensions.  Here\, I will devise an approach to image magnetic structures of centrosymmetric skyrmions grown from amorphous FeGePt; here\, internal Bloch domains with Néel caps can be reconstructed\, as predicted from micromagnetic simulations. For non-idealized emergent materials\, solving the atomic or magnetic structure in three dimensions can support results from density functional theory\, micromagnetic simulations and enable a deeper understanding of a system’s physical properties. \n_ \nContact : martien.den-hertog@neel.cnrs.fr
URL:https://sfp-alpes.fr/event/kayla-nguyen-oregon-university/
LOCATION:CNRS – Salle Erwin Bertaut (F418)\, CNRS - Institut Néel 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260911T110000
DTEND;TZID=Europe/Paris:20260911T120000
DTSTAMP:20260827T154120Z
CREATED:20260827T154120Z
LAST-MODIFIED:20260827T154120Z
UID:10000226-1789124400-1789128000@sfp-alpes.fr
SUMMARY:Alexander BRONSTEIN (Institute of Science & Technology\, Autriche)
DESCRIPTION:Experiment-guided generative models for protein structure and dynamics\nRésumé : \n\nProteins exist as a dynamic ensemble of multiple conformations\, and these motions are often crucial for their functions. However\, current structure prediction methods predominantly yield a single conformation\, overlooking the conformational heterogeneity revealed by diverse experimental modalities. I will present a framework for building experiment-grounded protein structure generative models that infer conformational ensembles consistent with measured experimental data. The key idea is to treat state-of-the-art protein structure predictors (e.g.\, AlphaFold3) as sequence-conditioned structural priors\, and cast ensemble modeling as posterior inference of protein structures given experimental measurements. Through extensive real-data experiments\, I will demonstrate the generality of our method to incorporate a variety of experimental measurements. In particular\, our framework uncovers previously unmodeled conformational heterogeneity from crystallographic densities\, and generates high-accuracy NMR ensembles orders of magnitude faster than the state-of-the-art and often better fitting the experimental data than the publicly deposited structures to the Protein Data Bank. I believe that this approach will unlock building predictive models that fully embrace experimentally observed conformational diversity.​\n_\n​\n\n\n\nLes séminaires et soutenances sont ouverts à tous\, notez toutefois que l’accès au campus EPN nécessite un avis de rendez-vous. Merci de remplir ce formulaire  et de l’adresser\, plus de 48h à l’avance\, à ce contact.\nPensez à vous munir d’une pièce d’identité le jour de votre visite.
URL:https://sfp-alpes.fr/event/alexander-bronstein-institute-of-science-technology-autriche/
LOCATION:IBS – Salle des séminaires\, IBS 71 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IBS":MAILTO:ibs.seminaires@ibs.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260911T110000
DTEND;TZID=Europe/Paris:20260911T120000
DTSTAMP:20260903T154443Z
CREATED:20260903T154413Z
LAST-MODIFIED:20260903T154443Z
UID:10000239-1789124400-1789128000@sfp-alpes.fr
SUMMARY:William FAUGNO (LKB)
DESCRIPTION:Topology in the Many-Body Spectrum: A Spectral Localizer Approach to Quantum Scars\nRésumé : \nTopological phases\, both single-particle and many-body\, are often formulated through momentum-space invariants\, many of which rely on the presence of a spectral gap. However\, disorder and gapless spectra can make these conventional approaches difficult to apply. The spectral localizer provides an alternative real-space framework for defining and characterizing topology in such settings. By combining the Hamiltonian with position operators\, it constructs a pseudospectrum that can identify topologically protected states while simultaneously providing a measure of their spectral stability. The spectral localizer has been successfully applied to a variety of single-particle systems\, including disordered and gapless systems. In this seminar\, I will present recent work extending the spectral localizer to many-body systems. Our construction provides a general pseudospectral framework for identifying topologically protected states throughout the many-body spectrum. We have used this framework to identify candidates for quantum many-body scarring in both an interacting chiral bosonic chain and the PXP model\, demonstrating that the approach is not tied to a particular microscopic mechanism for scarring. The many-body spectral localizer thus provides new insight into the structure and stability of these anomalous ETH-violating states\, while offering a quantitative measure of their stability. Finally\, I will discuss the implications of this framework for quantum error-correcting codes constructed from quantum many-body scar subspaces. \nContact : jeanne.colbois@neel.cnrs.fr \nLe séminaire théorie est financé par la fédération de recherche Quantalps.
URL:https://sfp-alpes.fr/event/william-faugno-lkb/
LOCATION:LPMMC – salle Roger Maynard (G421)\, CNRS - LPMMC 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260911T123000
DTEND;TZID=Europe/Paris:20260911T131500
DTSTAMP:20260827T150826Z
CREATED:20260827T150807Z
LAST-MODIFIED:20260827T150826Z
UID:10000222-1789129800-1789132500@sfp-alpes.fr
SUMMARY:Sandra LAVOREL (Laboratoire d’Écologie Alpine\, Grenoble)
DESCRIPTION:S’allier avec la nature pour l’adaptation au changement climatique\nRésumé : \nLes écosystèmes en bon état et leur biodiversité contribuent de multiples façons à la qualité de notre vie. Outre leur rôle dans la séquestration du carbone\, ils soutiennent l’adaptation au changement climatique par leur résilience\, la régulation des risques naturels ou le soutien du tissu économique et culturel. Les solutions fondées sur la nature mobilisent ces capacités par la conservation\, la gestion durable et la restauration de la biodiversité. Dans cette présentation vous verrez comment elles peuvent être mises en œuvre dans nos territoires\, en concertation avec leurs acteurs. \nÀ propos de l’intervenant : \nSandra Lavorel est directrice de recherche au CNRS. Elle est une figure majeure de l’écologie scientifique. Elle travaille au Laboratoire d’Écologie Alpine à Grenoble. Pionnière de l’écologie fonctionnelle des plantes\, ses recherches portent sur les effets du changement climatique et des usages des sols sur la biodiversité\, et le fonctionnement des écosystèmes. Elle applique ces approches à la quantification des services écosystémiques et à l’adaptation au changement climatique. Avec ses travaux interdisciplinaires et transdisciplinaires\, elle figure parmi les leaders mondiaux de l’analyse des trajectoires d’adaptation fondée sur la nature. Très impliquée dans le dialogue science-politique\, elle a contribué aux évaluations internationales (IPBES\, GIEC) et nationales (Evaluation Française des Ecosystème et des Services Ecosystémiques). \n_ \nContact : contact@giant-grenoble.org \n 
URL:https://sfp-alpes.fr/event/sandra-lavorel-laboratoire-decologie-alpine-grenoble/
LOCATION:Amphi Minatec\, 3 parvis Louis Néel\, Grenoble\, 38054\, France
CATEGORIES:Séminaire
ORGANIZER;CN="GIANT":MAILTO:giant.campus@cea.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260914T110000
DTEND;TZID=Europe/Paris:20260914T120000
DTSTAMP:20260910T140135Z
CREATED:20260910T140135Z
LAST-MODIFIED:20260910T140135Z
UID:10000241-1789383600-1789387200@sfp-alpes.fr
SUMMARY:Daniel DUFFY (Cambridge\, UK)
DESCRIPTION:Mechanics and geometry of nematic shape-morphing sheets\n\nRésumé : \nThin ‘shape-programmed’ sheets morph into curved shapes when stimulated by heat\, light\, or chemical fuel. Biology is full of intricate examples (leaves\, petals\, etc)\, and soft synthetic materials such as liquid-crystal elastomers have begun to approach similar levels of richness\, opening doors to bio-inspired soft machines. Such machines can lift\, pump\, push\, pull\, . . . etc\, promising myriad applications including microfluidic components\, deployable structures\, switchable surfaces\, and robotic actuators. I’ll present work on nematic shape morphers\, in which the direction of anisotropic deformation is patterned\, while deformation magnitudes are spatially uniform. The focus will be on encoding Gauss curvature\, which imparts mechanical strength to the resultant structures\, as Gauss understood centuries ago. The patterned deformation direction must typically be chosen at the time of manufacture\, leading to a design limitation: the morphing sheet can only realise a single target shape. I will then show how to overcome this limitation\, by varying the deformation magnitude (e.g. via patterned illumination) in both space and time. This new paradigm allows a single physical sample to be morphed into arbitrarily many different shapes at will. Thus a designer can specify entire time-dependent motions of the sheet. This capability could greatly increase the versatility of soft robots\, e.g. when operating in confined environments or performing complex tasks. Furthermore\, it facilitates swimming\, which typically requires non-reciprocal motion. More generally\, it unlocks the full potential of shape-morphing sheets\, allowing them to progress from being merely functional to being truly multi-functional. \n_ \nContact : emmanuel.siefert@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/daniel-duffy-cambridge-uk/
LOCATION:LiPhy – Salle de conférence\, LiPhy 140 avenue de la Physique\, St Martin d'Hères\, 38402\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260914T140000
DTEND;TZID=Europe/Paris:20260914T150000
DTSTAMP:20260903T152520Z
CREATED:20260903T152520Z
LAST-MODIFIED:20260903T152520Z
UID:10000237-1789394400-1789398000@sfp-alpes.fr
SUMMARY:Gabriel GARCIA JIMENEZ  (Institut Laue-Langevin)
DESCRIPTION:Proton-induced reactions on 238U in inverse kinematics : probing fission through nucleon knockout\nRésumé : \nIn this seminar\, I will present a study of proton-induced reactions on 238U in inverse kinematics\, performed at 540 AMeV with the R3B/SOFIA setup at GSI. The experiment provides access to the different reaction channels and\, in particular\, to the fission of the protactinium residue following nucleon knockout. \nI will discuss how the excitation energy of the residual nucleus was reconstructed from the kinematics of the emitted nucleons and how it can be correlated with the charge distribution of the fission fragments. This provides a way to investigate the evolution of shell effects with excitation energy and to test different theoretical descriptions of this process. The experimental results will be compared with calculations based on the INCL and ABLA07 models. \nFinally\, I will show the measured cross sections for the main spallation-evaporation and spallation-fission channels and compare them with previous experimental data and theoretical predictions. Overall\, the results provide insight into the interplay between nucleon knockout\, nuclear excitation\, and fission in relativistic proton-induced reactions on heavy nuclei. \nHenry Fischer (College 3 Secretary) \nExternal visitors may ask for a site access to : dubouloz@ill.fr \nZoom link : https://ill.zoom.us/j/7804743065?pwd=vYbib10VNk56W5mHOHB2QhzTBEyT0J.1&omn=95143035964 – Password : SeminarC3 \n 
URL:https://sfp-alpes.fr/event/gabriel-garcia-jimenez-institut-laue-langevin/
LOCATION:ILL – Salle de Séminaire (110-111)\, ILL 50 71 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260914T140000
DTEND;TZID=Europe/Paris:20260914T150000
DTSTAMP:20260910T141150Z
CREATED:20260910T141150Z
LAST-MODIFIED:20260910T141150Z
UID:10000242-1789394400-1789398000@sfp-alpes.fr
SUMMARY:Alberto CARTA ( Laboratory for Material simulations\, Paul Scherrer Institut\, Villigen)
DESCRIPTION:Of bandits and Bohr magnetons : balancing exploration and exploitation in magnetic landscapes\nRésumé : \nThe energy landscape of strongly interacting magnetic materials is a high-dimensional\, rugged terrain populated by a multitude of metastable states with distinct magnetizations\, oxidation states\, and orbital orders. Identifying the true ground state within this complexity remains a significant hurdle for the computational design of materials with tunable magnetic properties.\nBuilding on the work of Ponet et al. [1\,2]\, we systematically characterize this terrain to reveal the fundamental drivers of its complexity. We trace its origins to a core competition between the DFT functional’s preference for delocalization and the Hubbard +U correction’s drive for localization. This primary conflict is further modulated by a hierarchy of magnetic interactions\, including Hund’s coupling\, superexchange\, and Kugel-Khomskii physics\, which collectively define the energetic valleys and barriers across both high and low energy scales.\nTo overcome these barriers\, we propose a novel approach inspired by a completely different field: advertisement/recommendation engines (contextual Bandits) currently powering social media feeds and large parts of the Internet. By leveraging bandit strategies that balance the exploration of unknown configurations with the exploitation of known areas\, we demonstrate an efficient method for navigating this landscape. Our results show that these strategies successfully identify the lowest energy states where traditional methods often fail\, providing a robust framework for predicting and engineering the properties of strongly correlated magnetic materials. \n[1] Ponet\, L.\, Di Lucente\, E.\, & Marzari\, N. (2024). The energy landscape of magnetic materials. npj Computational Materials\, 10(1)\, 151.\n[2] Haddadi\, F.\, Campi\, D.\, dos Santos\, F.\, Mounet\, N.\, Ponet\, L.\, Marzari\, N.\, & Gibertini\, M. (2025). Exploring the magnetic landscape of easily-exfoliable two-dimensional materials (arXiv:2509.09531v2). \n_ \nContact : matteo.dastuto@neel.cnrs.fr
URL:https://sfp-alpes.fr/event/alberto-carta-laboratory-for-material-simulations-paul-scherrer-institut-villigen/
LOCATION:CNRS – Salle Louis Weil (E424)\, CNRS - Institut Néel 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260915T110000
DTEND;TZID=Europe/Paris:20260915T120000
DTSTAMP:20260910T142118Z
CREATED:20260910T142118Z
LAST-MODIFIED:20260910T142118Z
UID:10000243-1789470000-1789473600@sfp-alpes.fr
SUMMARY:Thomas KISBY (Centre for Nanotechnology in Medicine\, Manchester (UK)
DESCRIPTION:Nanoscale approaches to brain tumour therapy : harnessing biology for targeted therapeutics\nRésumé : \nGlioblastoma remains one of the most challenging cancers to treat\, in part because conventional approaches struggle to selectively access and target the cells responsible for recurrence. This talk will explore how nanoscale technologies can exploit the biology of brain tumours and the brain to create new therapeutic opportunities. Using graphene oxide\, a nanomaterial with preferential interaction with tumour-associated immune cells\, I will describe how we can use this as a locally administered platform for both more localised chemotherapy and targeted tumour immunomodulation. \nI will then discuss a new approach that exploits the biological response to tumour resection itself : a transient postoperative window in which the blood–brain barrier becomes selectively\npermeable to clinically used liposomal nanomedicines. By linking the timing and biology of surgery with nanoscale drug delivery\, we have developed an approach to specifically target residual disease at the site of recurrence. Together\, these studies illustrate how understanding and exploiting biological processes can guide the design and application of nanotherapeutics for brain cancer. \n_ \nContact : anne-laure.bulin@univ-grenoble-aleps.fr
URL:https://sfp-alpes.fr/event/thomas-kisby-centre-for-nanotechnology-in-medicine-manchester-uk/
LOCATION:IAB – Salle de séminaire\, IAB Site Santé - Allée des Alpes\, La Tronche\, 38700\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IAB":MAILTO:appaixfl@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260918T100000
DTEND;TZID=Europe/Paris:20260918T110000
DTSTAMP:20260828T133335Z
CREATED:20260828T133107Z
LAST-MODIFIED:20260828T133335Z
UID:10000233-1789725600-1789729200@sfp-alpes.fr
SUMMARY:Sandrine GERBER (Deputy Director of the Institute of Chemical Sciences and Engineering (ISIC) at EPFL) -  Franck LEBRIN (PhD​ Director of an international Inserm JointLab at Leiden University Medical Center​ (LUMC\, Department of Internal Medicine))
DESCRIPTION:1) Multifunctional harmonic nanoparticles for targeted bioimaging and drug delivery.\n\n\n​​​​​​​2) Targeting pericytes for microvascular stabilization.\nRésumé : \n\nSandrine GERBER\nIs e​xpert in organic synthesis\, engineering of polymer and lipid-based nanoparticles for gene delivery\, surface functionalization of nanomaterials for theranostic applications as well as DNA biosensors for viral screening.\nThe research program of her group is devoted to the development of new chemical entities for bio-applications. Her team is mainly interested in the design\, synthesis and evaluation of functionalized nanomaterials and biomaterials for therapeutic applications as imaging probes\, drug nanocarriers and biosensors. In particular\, harmonic nanoparticles are bioconjugated to cancer targeting ligands\, caged therapeutic cargos and complementary contrast agents to develop new theranostic tools. Chitosan-based copolymers are engineered for the delivery of plasmid DNA and siRNA in the context of liver metabolic diseases and oncology. The functionalization of glass slides and gold interdigitated electrodes with peptide- and polymer-based spacers is used for the development of DNA biosensors for viral screening.​\n​\nFranck LEBRIN\n​Is a vascular biologist​ and a member of Inserm Abroad. His research focuses on microvascular disorders\, particularly Hereditary Hemorrhagic Telangiectasia (HHT)\, with an emphasis on endothelial–pericyte interactions. He develops advanced human hiPSC- and mouse-based models\, combined with ultrasound imaging\, to investigate disease mechanisms and support translational research. His work has contributed to the development of AKT inhibitors currently in Phase I and III clinical trials\, as well as small molecules promoting vessel stability and integrity for HHT and pericyte-related diseases affecting the brain\, eye\, and kidney. He is Vice-Chair of Cure HHT International and founder of RougeTX\, a spin-off developing pericyte-focused therapies.​\n\n\n_\n\n\n\n\n\nATTENTION ! L’accès à Clinatec est réservé aux porteurs de laissez-passer CEA
URL:https://sfp-alpes.fr/event/sandrine-gerber-deputy-director-of-the-institute-of-chemical-sciences-and-engineering-isic-at-epfl-franck-lebrin-phd-director-of-an-international-inserm-jointlab-at-leiden-university/
LOCATION:Clinatec\, amphithéâtre\, 17\, avenue des Martyrs\, Grenoble\, 38000\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IRIG - CEA":MAILTO:irig.communication@cea.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260918T110000
DTEND;TZID=Europe/Paris:20260918T120000
DTSTAMP:20260910T150555Z
CREATED:20260910T150555Z
LAST-MODIFIED:20260910T150555Z
UID:10000244-1789729200-1789732800@sfp-alpes.fr
SUMMARY:Yuzhu WANG (LPMMC)
DESCRIPTION:Geometric excitations in topological flat bands\nLe séminaire théorie est financé par la fédération de recherche Quantalps. \nRésumé : \nGeometric excitations provide a new way of probing the internal structure of fractional quantum Hall (FQH) states beyond their more familiar topological properties. In this talk\, we will focus on a particular class of such excitations\, known as graviton modes\, and ask how their physics changes when we move from Landau levels to fractional Chern insulators (FCIs). \nWe will start with a brief introduction to the basic concepts and formalisms used to describe FQH states\, with an emphasis on the guiding center degree of freedom and its connection to quantum geometry. This will provide the background for understanding the microscopic origin of graviton modes and how they can be identified in strongly correlated topological bands. We then turn to FCIs\, where an intriguing contrast can be found. Despite the absence of continuous rotational symmetry in the underlying lattice\, both the FCI ground state and the graviton mode exhibit an emergent guiding center rotational symmetry. The excitation continuum\, however\, does not share this symmetry. This mismatch allows the graviton mode to couple much more strongly to the continuum\, giving it a much shorter lifetime than in Landau levels. We will introduce a simple microscopic model that helps explain why this happens. \nFinally\, we will discuss how the graviton mode may be enhanced and detected experimentally in moiré materials\, and what kinds of tuning strategies could make it more visible. We will also briefly discuss how this picture can be generalized beyond spin-two graviton modes to geometric excitations with higher spins and what exciting physics can be expected there. \n_ \nContact : cecile.repellin@lpmmc.cnrs.fr 
URL:https://sfp-alpes.fr/event/yuzhu-wang-lpmmc/
LOCATION:LPMMC – salle Roger Maynard (G421)\, CNRS - LPMMC 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260918T110000
DTEND;TZID=Europe/Paris:20260918T120000
DTSTAMP:20260910T151054Z
CREATED:20260910T151054Z
LAST-MODIFIED:20260910T151054Z
UID:10000245-1789729200-1789732800@sfp-alpes.fr
SUMMARY:Wilson POON (University of Edinburgh\, UK)
DESCRIPTION:Cooking crystalline candies and the ductile to brittle transition in concentrated suspensions\nRésumé : \nThe existence and origin of the ductile to brittle transition in non-Brownian suspensions and pastes is under-explored despite the ubiquity of such materials in practical applications. We demonstrate the phenomenon in candies of sugar crystals in a water-protein-fat matrix prepared by boiling a sugar-cream-butter mixture (known as `fudge’ in some countries). As cooking time or final cooking temperature increases\, we observe a transition from a fluid to a ductile solid\, then to a brittle solid that abruptly fractures in compression. We propose that this is driven by rising solid sugar crystal volume fraction\, and indeed find the same sequence of behaviour in a suspension of non-Brownian calcite particles as the solid fraction moves from frictional jamming to random close packing. Particle-based simulations reveal the sensitivity of the observed phenomenon to boundary conditions. \n_ \nContact : samantha.micciulla@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/wilson-poon-university-of-edinburgh-uk/
LOCATION:LiPhy – Salle de conférence\, LiPhy 140 avenue de la Physique\, St Martin d'Hères\, 38402\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260922T103000
DTEND;TZID=Europe/Paris:20260922T113000
DTSTAMP:20260917T141914Z
CREATED:20260917T141914Z
LAST-MODIFIED:20260917T141914Z
UID:10000256-1790073000-1790076600@sfp-alpes.fr
SUMMARY:1) João BORGES (University of Aveiro\, Portugal)  - 2) Dominique VAUTIER (Université de Strasbourg – Centre de Recherche en Biomédecine de Strasbourg)
DESCRIPTION:1) Supramolecular design of cell-instructive materials for regenerative medicine strategies.\n2) Les forces intracellulaires dans le remodelage de la chromatine : mécanotransduction directe et inversée​.\nRésumé : \nThese two presentations will provide complementary perspectives on how cells interact with and respond to their physical and material environment\, from the design of cell-instructive biomaterials to the role of intracellular forces in chromatin remodeling.\n\nThey will be followed in the afternoon by Nathan Thibieroz’s Phd defence at 14:00\, on his work at GreEn-ER – Amphithéâtre 2A003\n\n_\n\n\n\n​ATTENTION ! L’accès au CEA​ est réservé aux porteurs de laissez-passer. Merci de contacter au préalable Elisa Migliorini​
URL:https://sfp-alpes.fr/event/1-joao-borges-university-of-aveiro-portugal-2-dominique-vautier-universite-de-strasbourg-centre-de-recherche-en-biomedecine-de-strasbourg/
LOCATION:CEA – Salle de séminaire IRIG (104 – bâtiment C3)\, 17\, avenue des Martyrs\, Grenoble\, 38000\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IRIG - CEA":MAILTO:irig.communication@cea.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260922T140000
DTEND;TZID=Europe/Paris:20260922T150000
DTSTAMP:20260910T151656Z
CREATED:20260910T151623Z
LAST-MODIFIED:20260910T151656Z
UID:10000246-1790085600-1790089200@sfp-alpes.fr
SUMMARY:Joseph KIOSEOGLOU (Department of Physics\, Aristotle University of Thessaloniki\, Greece)
DESCRIPTION:Atomistic & AI Discovery of Functional Nanomaterials & Thin Films\nRésumé : \nFunctional nanomaterials and thin films play a central role in emerging technologies for microelectronics\, optoelectronics\, energy conversion\, sensing\, and health-related applications. Their properties are often governed by atomic-scale mechanisms\, including defects\, dopant incorporation\, surface and interface stability\, strain fields\, morphology evolution\, growth pathways\, and phase transformations. In this seminar\, predictive atomistic modelling strategies will be presented as a way to connect these mechanisms with experimentally measurable properties and data-driven materials design. Selected examples will include semiconductors\, oxide materials\, nanowires\, nanoparticles\, low-dimensional systems\, and bio-related/pharmaceutical materials\, with emphasis on first-principles calculations\, molecular dynamics\, interatomic potentials\, machine-learning interatomic potentials\, and microscopy-informed simulations. Recent opportunities opened by artificial intelligence and generative modelling\, including sustainable-by-design materials discovery\, will also be discussed. These approaches enable the exploration of large chemical and structural spaces\, the simultaneous optimization of multiple properties\, and the proposal of experimentally relevant candidate materials. The broader perspective is to show how computation can move beyond interpretation and become part of a predictive\, collaborative workflow integrating modelling\, synthesis\, characterization\, and materials optimization for next-generation functional materials. \nShort Bio/CV\nPr. Joseph Kioseoglou research focuses on atomistic modelling\, first-principles calculations\, molecular dynamics\, machine-learning interatomic potentials\, and AI-assisted materials design\, with applications to semiconductors\, oxide materials\, nanostructures\, thin films\, surfaces\, interfaces\, defects\, nanoparticles\, and bio-related/pharmaceutical materials. He has coordinated and participated in numerous European and national research projects and has extensive experience in doctoral supervision\, international scientific collaborations and conference organization. He has held visiting professor/research positions in France\, Germany\, Japan\, including Grenoble INP/LMGP. \n_ \nContact : deborah.verger@grenoble-inp.fr
URL:https://sfp-alpes.fr/event/joseph-kioseiglou-department-of-physics-aristotle-university-of-thessaloniki-greece/
LOCATION:LMGP – salle des séminaires\, Grenoble INP -Phelma 3 parvis Louis Néel\, Grenoble\, 38054\, France
CATEGORIES:Séminaire
ORGANIZER;CN="LMGP":MAILTO:deborah.verger@grenoble-inp.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260922T140000
DTEND;TZID=Europe/Paris:20260922T150000
DTSTAMP:20260917T152447Z
CREATED:20260917T152447Z
LAST-MODIFIED:20260917T152447Z
UID:10000260-1790085600-1790089200@sfp-alpes.fr
SUMMARY:Klaus ENSSLIN (ETH Zürich)
DESCRIPTION:Bilayer graphene : rich in physics and good for devices\nRésumé : \nElectrons have a charge and a spin degree of freedom. The primitive unit cell in graphene honeycomb lattice has 2 atoms. As a consequence\, there is an additional valley degree of freedom in graphene that can be tuned by gate voltages. For electrostatically-defined quantum dots in bilayer graphene this leads to a particular filling sequence\, with the first 4 electrons in the s-shell and the next 8 electrons in the p-shell. The details of the level spectrum reveals many surprises\, such as a singly-degenerate spin-triplet/valley-singlet states for the two carrier state. When building a qubit\, one can utilize all available degrees of freedom: charge\, spin and valley. For the so-called Kramers qubits\, where spin and valley need to be flipped for relaxation from the excited to the ground state\, lifetimes as long as 100 s have been experimentally observed. For graphene layer twisted at the magic angle one can fabricate superconducting devices such as Josephson junctions\, SQUIDs and Cooper pairs boxes. In this talk I will present the prospects that graphene offers to investigate physics questions related to topology\, superconductivity\, spin-orbit interactions and spin-valley coupling as well as device concepts with unprecedented tuning opportunities. \n_ \n\n\n\nATTENTION : Pour accéder au site du CNRS (sans badge)\, envoyez-nous un e-mail plus de 24 heures avant le séminaire.\nATTENTION : To enter the CNRS site (without a badge)\, send us an email more than 24 hours before the seminar.\n\n\n\nContact : equipe-seminaires-nano@listes.grenoble.cnrs.fr
URL:https://sfp-alpes.fr/event/klaus-ensslin-eth-zurich/
LOCATION:CNRS – Salle Rémy Lemaire (K223)\, CNRS - Institut Néel 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260924T100000
DTEND;TZID=Europe/Paris:20260924T110000
DTSTAMP:20260917T151916Z
CREATED:20260917T151850Z
LAST-MODIFIED:20260917T151916Z
UID:10000259-1790244000-1790247600@sfp-alpes.fr
SUMMARY:Laura B. STEREN (Instituto de Nanociencia y Nanotecnologia CNEA/CONICET\, Buenos Aires\, Argentina)
DESCRIPTION:Emergent phenomena at Oxides surface and Interfaces\nRésumé : \nComplex oxides exhibit a rich variety of optical\, electronic\, and magnetic behaviours. When these materials are confined to the nanoscale\, they can display interfacial and size-dependent effects that are not present in bulk materials. The ability to design and fabricate artificial oxide heterostructures with tailored functionalities has therefore made them an important platform within the broader field of quantum materials. In this talk\, I will present our most recent results in oxide spintronics\, describe the main research directions pursued by our team\, and discuss the experimental challenges of controlling these materials at the nanometre scale\, where structure\, interfaces\, and functionality must be precisely managed to advance future oxide-based spintronic technologies. \n_ \nCollege 5B Secretary \nEdmond CHAN \nExternal visitors may ask for a site access to Brigitte Dubouloz (dubouloz@ill.fr)
URL:https://sfp-alpes.fr/event/laura-b-steren-instituto-de-nanociencia-y-nanotecnologia-cnea-conicet-buenos-aires-argentina/
LOCATION:ILL 50 building – room 101\, EPN Campus - 71 avenue des Martyrs\, Grenoble\, 38000\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260924T113000
DTEND;TZID=Europe/Paris:20260924T123000
DTSTAMP:20260917T150745Z
CREATED:20260917T150745Z
LAST-MODIFIED:20260917T150745Z
UID:10000258-1790249400-1790253000@sfp-alpes.fr
SUMMARY:Jérémie POSCHMANN (Université de Nantes)
DESCRIPTION:Functional genomics of brain disease : linking regulatory mechanisms\, circulating immune states and clinical trajectories\nRésumé : \nMy research uses func-onal genomics to characterize disease associated molecular states and to understand how they relate to biological mechanisms\, clinical heterogeneity and patient trajectories. I first used functional genomics directly in human brain tissue to identify regulatory alterations associated with disease. In autism spectrum disorder\, genome wide profiling revealed that clinically and genetically heterogeneous patients nevertheless shared convergent changes in regulatory activity. Subsequent studies in other brain disorders showed that this convergence at the molecular level was a recurrent feature and established functional genomics as a powerful approach to resolve disease-associated regulatory states. I subsequently extended this approach to circulating cells\, with the objective of accessing disease associated molecular states in living patients. In severe brain injury and psychiatric disorders\, our studies identified\nimmune and regulatory signatures associated with clinical trajectories and disease severity. These results support the use of circulating immune states to characterize biological heterogeneity beyond conventional diagnostic categories and provide a basis for patient stratification. A complementary programme in genetically defined neurodevelopmental disorders allows us to investigate these molecular alterations in a causal framework. By profiling patient blood cells carrying pathogenic variants in chromatin and proteostasis regulators\, we can connect a defined genetic alteration to its molecular consequences and to disease-relevant cellular pathways. \nTogether\, these studies establish a func-onal genomics framework that links regulatory mechanisms to accessible biomarkers and clinical trajectories in neurological and psychiatric disease. \n_ \nContact : yury.lages@univ-grenoble-alpes.fr ou sebastien.carnicella@univ-grenoble-alpes.fr \n 
URL:https://sfp-alpes.fr/event/jeremie-poschmann-universite-de-nantes/
LOCATION:GIN – Amphi Serge Kampf\, Grenoble Institut des Neurosciences (GIN) Bât. Edmond J. Safra\, Chemin Fortune Ferrini CHU\, La Tronche\, 38700\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260924T140000
DTEND;TZID=Europe/Paris:20260924T150000
DTSTAMP:20260827T153130Z
CREATED:20260827T153130Z
LAST-MODIFIED:20260827T153130Z
UID:10000225-1790258400-1790262000@sfp-alpes.fr
SUMMARY:Alexandre BERNARD (Walter Schottky Institute\, TU Munich)
DESCRIPTION:Remanent anomalous Hall effect from dual spin-orbit and exchange proximity in graphene heterostructure\nRésumé : \nThe coexistence of induced spin-orbit coupling (SOC) and magnetic exchange fields is predicted to drive graphene into topological phases\, such as the quantum anomalous Hall state. In this talk\, I will discuss the prospect of using monolayer graphene proximitized by WSe2 (SOC) and Cr2Ge2Te6 (magnetic exchange) to reach such “ex-so-tic” states. Low-temperature magnetotransport measurements of the heterostructures reveal a large and gate-tunable remanent anomalous Hall effect (AHE) persisting at zero magnetic field. Combining data analysis over various magnetic field ranges and a simple model\, we explain our findings by an intrinsic AHE regime\, where Berry curvature hot-spots from the interplay of SOC and magnetism dominate the Hall response\, but disorder broadening prevents quantization and a full topological phase transition. These results demonstrate the potential of double proximity effects in graphene-based van der Waals heterostructures as a route toward gate-tunable topological graphene phases and devices based on chiral edge states. \n_ \nContact : florence.levy-bertrand@neel.cnrs.fr \n 
URL:https://sfp-alpes.fr/event/alexandre-bernard-walter-schottky-institute-tu-munich/
LOCATION:CNRS – Salle Rémy Lemaire (K223)\, CNRS - Institut Néel 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260925T110000
DTEND;TZID=Europe/Paris:20260925T120000
DTSTAMP:20260827T154550Z
CREATED:20260827T154550Z
LAST-MODIFIED:20260827T154550Z
UID:10000227-1790334000-1790337600@sfp-alpes.fr
SUMMARY:Toyoyuki OSE (Hokkaido University\, Japon​)
DESCRIPTION:Viral strategies for immune evasion targeting the JAK-STAT pathway\nRésumé : \n\nThe capacity of viruses to target and inhibit immune signaling by the principal antiviral cytokines\, interferons (IFNs)\, is critical to the outcomes of infection and disease\, and is mediated by viral IFN-antagonist proteins. We have been working on viral IFN-antagonists from the order Mononegavirales such as genus Lyssavirus (e.g.\, rabies virus) and Morbillivirus (e.g.\, measles virus) that counteract the JAK-STAT system. STAT family members mediate signaling in the JAK–STAT pathway and are activated by phosphorylation at a conserved tyrosine residue\, resulting in dimerization through reciprocal interactions between the phosphotyrosine and a SH2 domain.\nTyrosine-phosphorylated STAT (pY-STAT) then translocates to the nucleus to induce the expression of genes encoding antiviral proteins. Although the active and functional forms of STATs are conventionally considered to be dimers\, STATs can undergo higher-order oligomerization\, which is implicated in regulating transcriptional activity. \nWe presented the cryo-EM structures of the tetrameric form of intact pY-STAT1 in complex with DNA or the P protein of rabies viruses [1\,2]. We explained the molecular architecture of the interactions by which P protein selectively antagonizes phosphorylated\, activated STAT1. This novel binding mode explains previously undefined mechanisms by which P protein inhibits importin binding\, DNA binding\, and the conformational transition of activated STAT1 into its DNA-binding form\, thus efficiently shutting down antiviral signaling. We also clarified that the C-terminal domain of the V protein from measles virus selectively binds to the core-region of STAT2 but not STAT13. We were able to monitor that binding of V and IRF9 to STAT2-core is competitive ; V disrupts a preformed STAT2–IRF9 interaction\, suggesting a new mechanism by which V can prevent type I IFN signaling by preventing STAT1–STAT2–IRF9 (the ISGF3 complex) formation [3\,4]. Taken together\, our findings substantially advance molecular understanding of viral evasion of antiviral immunity\, with high resolution molecular insights having the potential to inform novel intervention strategies for a lethal viral disease. \n1. Rabies virus antagonizes interferon signaling by targeting phosphorylated STAT1 tetramers. bioRxiv 2026.07.29.741124 (2026) doi:10.64898/2026.07.29.741124.\n2. Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein. Sci. Signal. 18\, eads2210 (2025).\n3. The Measles Virus V Protein Binding Site to STAT2 Overlaps That of IRF9. J. Virol. 94\, e01169-20 (2020).\n4. Solution structure of the C-terminal domain of the measles virus V protein in its free form and mechanistic analysis of STAT2 targeting. J. Virol. 99\, e00739-25 (2025).​ \n_\n\n\n\n\nLes séminaires et soutenances sont ouverts à tous\, notez toutefois que l’accès au campus EPN nécessite un avis de rendez-vous. Merci de remplir ce formulaire  et de l’adresser\, plus de 48h à l’avance\, à ce contact.\nPensez à vous munir d’une pièce d’identité le jour de votre visite.
URL:https://sfp-alpes.fr/event/toyoyuki-ose-hokkaido-university-japon/
LOCATION:IBS – Salle des séminaires\, IBS 71 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IBS":MAILTO:ibs.seminaires@ibs.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260929T140000
DTEND;TZID=Europe/Paris:20260929T150000
DTSTAMP:20260910T152942Z
CREATED:20260910T152942Z
LAST-MODIFIED:20260910T152942Z
UID:10000248-1790690400-1790694000@sfp-alpes.fr
SUMMARY:Natali PLANK (School of Chemical and Physical Sciences and the MacDiarmid Institute for Advanced Materials and Nanotechnology\, Victoria University of Wellington\, New Zealand)
DESCRIPTION:Nanowire and carbon nanotube device structures for Biosensors and Artificial Neural Networks\nRésumé : \nCarbon nanotube (CNT) networks offer a particularly attractive platform due to their simple fabrication\, tunable electronic properties\, and ability to be interrogated through multiple electrical contacts on a single chip [1]. Functionalised carbon nanotube and graphene field effect transistors (CNTFETs and GFETs) have been used as the active channel in biosensors\, with the future promise of lab-on-a-chip diagnostics strongly motivating the research [2]. The ability to effectively sense analytes depends on multiple factors\, the conductivity of the platform [3]\, the robustness of the functionalisation and the selectivity and function of the receptor [4]. \nCarbon nanotubes also offer an interesting base platform for neuromorphic computing via physical reservoirs. Physical reservoir computing exploits the intrinsic dynamics of complex materials to perform temporal information processing with low power consumption and minimal training requirements. Disordered networks of memristive nanowires have emerged as promising neuromorphic architectures\, as they can host large numbers of nonlinear junctions that collectively generate rich spatiotemporal dynamics [5-7]. \nHere I will present our recent work on the development of the CNTFET and GFET platforms with aptamers and insect odorant receptors and the different challenges and device constraints we have encountered. I will also present our work on the development of the CNT platform for physical reservoir computing applications. \n[1]      Topinka\, M. A\, et al. Nano Lett. 2009 9\, 1866–1871 \n[2]      T An et al\, Lab Chip\, 2010\,10\,2052-2056 \n[3]      M Thanihaichelvan M\, et al\, Biosensors and Bioelectronics\, 2019\, 130\, 408-413 \n[4]      Nguyen et al.\, Nanomaterials\, 2021 11 (9)\, 2280 \n[5]      Milano\, G\, et al. Nat. Mater. 2022\, 21 (2)\, 195–202. \n[6]      Kotooka\, T.\, et al. Thermally Stable Ag 2 Se Nanowire Network as an Effective In-Materio Physical Reservoir Computing Device. 2024\, 2400443\, 1–10.  \n[7]      Zhu\, R.\, et al Online Dynamical Learning and Sequence Memory with Neuromorphic Nanowire Networks. Nat. Commun. 2023\, 14 (1)\, 6697.  \n\nShort Bio/CV\nDr Natalie Plank is Deputy Director for Commercialisation and Industry Engagement and an Associate Professor in Physics in the School of Chemical and Physical Sciences at Victoria University of Wellington. Natalie completed a BSc (Hons) in Astrophysics at The University of Edinburgh before doing an MSc in Microelectronics. She then completed her PhD on the functionalisation of carbon nanotubes for molecular electronics with Rebecca Cheung also at The University of Edinburgh. \nNatalie’s research interests are in the area of nanomaterial device fabrication and the characterisation of novel materials. Her current work focuses on nanomaterial device platforms for sensing technology and artificial neural networks. She is interested in carbon nanotubes and ZnO nanowires for nanowire transistor applications and in particular the ability to functionalise the nanomaterial channels with specific biomarkers or memristive molecules. Natalie’s core interests are in low cost fabrication techniques which allow for high throughput of devices whilst maintaining the particular material properties of the unique nanowire system. \n_ \nContact : deborah.verger@grenoble-inp.fr
URL:https://sfp-alpes.fr/event/natali-plank-school-of-chemical-and-physical-sciences-and-the-macdiarmid-institute-for-advanced-materials-and-nanotechnology-victoria-university-of-wellington-new-zealand/
LOCATION:LMGP – salle des séminaires\, Grenoble INP -Phelma 3 parvis Louis Néel\, Grenoble\, 38054\, France
CATEGORIES:Séminaire
ORGANIZER;CN="LMGP":MAILTO:deborah.verger@grenoble-inp.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261001T130000
DTEND;TZID=Europe/Paris:20261001T140000
DTSTAMP:20260917T134744Z
CREATED:20260917T134744Z
LAST-MODIFIED:20260917T134744Z
UID:10000255-1790859600-1790863200@sfp-alpes.fr
SUMMARY:Alice CLEYNEN (LJK\, Grenoble)
DESCRIPTION:Les différentes facettes de l’ARN : les opportunités ouvertes par le séquençage direct par nanopore\nRésumé : \nLe séquençage direct de l’ARN (Direct RNA Sequencing\, DRS) par nanopore (Oxford Nanopore Technologies) est une technologie qui lit les molécules d’ARN telles qu’elles existent dans la cellule\, sans jamais les copier. Cette absence d’amplification change la donne à plusieurs titres : elle évite les biais d’estimation de l’abondance des ARN inhérents à toute étape de PCR\, et surtout elle préserve les modifications chimiques qui décorent nativement les molécules — des marques aujourd’hui reconnues comme un véritable langage réactionnel. Autre atout\, les lectures produites (des « long-reads ») couvrent la molécule dans son intégralité\, ce qui permet d’assigner directement chaque lecture à un isoforme\, plutôt que de devoir les reconstruire a posteriori à partir de données au niveau du gène. Cerise sur le gâteau\, le DRS donne aussi accès à la longueur de la queue poly(A)\, dont un nombre croissant d’études souligne le rôle déterminant dans la stabilité et la traduction des ARN. \n_ \nContact : lucie.lamothe@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/alice-cleynen-ljk-grenoble/
LOCATION:IMAG – Salle de Réunion\, 150 place du Torrent\, St Martin d’Hères\, 38400\, France
CATEGORIES:Séminaire
ORGANIZER;CN="TIMC - IMAG":MAILTO:lucie.lamothe@univ-grenoble-alpes.fr
END:VEVENT
END:VCALENDAR