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X-WR-CALDESC:Évènements pour SFP Alpes
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DTSTART;TZID=Europe/Paris:20260918T100000
DTEND;TZID=Europe/Paris:20260918T110000
DTSTAMP:20260828T133335Z
CREATED:20260828T133107Z
LAST-MODIFIED:20260828T133335Z
UID:10000233-1789725600-1789729200@sfp-alpes.fr
SUMMARY:Sandrine GERBER (Deputy Director of the Institute of Chemical Sciences and Engineering (ISIC) at EPFL) -  Franck LEBRIN (PhD​ Director of an international Inserm JointLab at Leiden University Medical Center​ (LUMC\, Department of Internal Medicine))
DESCRIPTION:1) Multifunctional harmonic nanoparticles for targeted bioimaging and drug delivery.\n\n\n​​​​​​​2) Targeting pericytes for microvascular stabilization.\nRésumé : \n\nSandrine GERBER\nIs e​xpert in organic synthesis\, engineering of polymer and lipid-based nanoparticles for gene delivery\, surface functionalization of nanomaterials for theranostic applications as well as DNA biosensors for viral screening.\nThe research program of her group is devoted to the development of new chemical entities for bio-applications. Her team is mainly interested in the design\, synthesis and evaluation of functionalized nanomaterials and biomaterials for therapeutic applications as imaging probes\, drug nanocarriers and biosensors. In particular\, harmonic nanoparticles are bioconjugated to cancer targeting ligands\, caged therapeutic cargos and complementary contrast agents to develop new theranostic tools. Chitosan-based copolymers are engineered for the delivery of plasmid DNA and siRNA in the context of liver metabolic diseases and oncology. The functionalization of glass slides and gold interdigitated electrodes with peptide- and polymer-based spacers is used for the development of DNA biosensors for viral screening.​\n​\nFranck LEBRIN\n​Is a vascular biologist​ and a member of Inserm Abroad. His research focuses on microvascular disorders\, particularly Hereditary Hemorrhagic Telangiectasia (HHT)\, with an emphasis on endothelial–pericyte interactions. He develops advanced human hiPSC- and mouse-based models\, combined with ultrasound imaging\, to investigate disease mechanisms and support translational research. His work has contributed to the development of AKT inhibitors currently in Phase I and III clinical trials\, as well as small molecules promoting vessel stability and integrity for HHT and pericyte-related diseases affecting the brain\, eye\, and kidney. He is Vice-Chair of Cure HHT International and founder of RougeTX\, a spin-off developing pericyte-focused therapies.​\n\n\n_\n\n\n\n\n\nATTENTION ! L’accès à Clinatec est réservé aux porteurs de laissez-passer CEA
URL:https://sfp-alpes.fr/event/sandrine-gerber-deputy-director-of-the-institute-of-chemical-sciences-and-engineering-isic-at-epfl-franck-lebrin-phd-director-of-an-international-inserm-jointlab-at-leiden-university/
LOCATION:Clinatec\, amphithéâtre\, 17\, avenue des Martyrs\, Grenoble\, 38000\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IRIG - CEA":MAILTO:irig.communication@cea.fr
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260918T110000
DTEND;TZID=Europe/Paris:20260918T120000
DTSTAMP:20260910T150555Z
CREATED:20260910T150555Z
LAST-MODIFIED:20260910T150555Z
UID:10000244-1789729200-1789732800@sfp-alpes.fr
SUMMARY:Yuzhu WANG (LPMMC)
DESCRIPTION:Geometric excitations in topological flat bands\nLe séminaire théorie est financé par la fédération de recherche Quantalps. \nRésumé : \nGeometric excitations provide a new way of probing the internal structure of fractional quantum Hall (FQH) states beyond their more familiar topological properties. In this talk\, we will focus on a particular class of such excitations\, known as graviton modes\, and ask how their physics changes when we move from Landau levels to fractional Chern insulators (FCIs). \nWe will start with a brief introduction to the basic concepts and formalisms used to describe FQH states\, with an emphasis on the guiding center degree of freedom and its connection to quantum geometry. This will provide the background for understanding the microscopic origin of graviton modes and how they can be identified in strongly correlated topological bands. We then turn to FCIs\, where an intriguing contrast can be found. Despite the absence of continuous rotational symmetry in the underlying lattice\, both the FCI ground state and the graviton mode exhibit an emergent guiding center rotational symmetry. The excitation continuum\, however\, does not share this symmetry. This mismatch allows the graviton mode to couple much more strongly to the continuum\, giving it a much shorter lifetime than in Landau levels. We will introduce a simple microscopic model that helps explain why this happens. \nFinally\, we will discuss how the graviton mode may be enhanced and detected experimentally in moiré materials\, and what kinds of tuning strategies could make it more visible. We will also briefly discuss how this picture can be generalized beyond spin-two graviton modes to geometric excitations with higher spins and what exciting physics can be expected there. \n_ \nContact : cecile.repellin@lpmmc.cnrs.fr 
URL:https://sfp-alpes.fr/event/yuzhu-wang-lpmmc/
LOCATION:LPMMC – salle Roger Maynard (G421)\, CNRS - LPMMC 25 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
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DTSTART;TZID=Europe/Paris:20260918T110000
DTEND;TZID=Europe/Paris:20260918T120000
DTSTAMP:20260910T151054Z
CREATED:20260910T151054Z
LAST-MODIFIED:20260910T151054Z
UID:10000245-1789729200-1789732800@sfp-alpes.fr
SUMMARY:Wilson POON (University of Edinburgh\, UK)
DESCRIPTION:Cooking crystalline candies and the ductile to brittle transition in concentrated suspensions\nRésumé : \nThe existence and origin of the ductile to brittle transition in non-Brownian suspensions and pastes is under-explored despite the ubiquity of such materials in practical applications. We demonstrate the phenomenon in candies of sugar crystals in a water-protein-fat matrix prepared by boiling a sugar-cream-butter mixture (known as `fudge’ in some countries). As cooking time or final cooking temperature increases\, we observe a transition from a fluid to a ductile solid\, then to a brittle solid that abruptly fractures in compression. We propose that this is driven by rising solid sugar crystal volume fraction\, and indeed find the same sequence of behaviour in a suspension of non-Brownian calcite particles as the solid fraction moves from frictional jamming to random close packing. Particle-based simulations reveal the sensitivity of the observed phenomenon to boundary conditions. \n_ \nContact : samantha.micciulla@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/wilson-poon-university-of-edinburgh-uk/
LOCATION:LiPhy – Salle de conférence\, LiPhy 140 avenue de la Physique\, St Martin d'Hères\, 38402\, France
CATEGORIES:Séminaire
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