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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260504T110000
DTEND;TZID=Europe/Paris:20260504T120000
DTSTAMP:20260430T115259Z
CREATED:20260430T115259Z
LAST-MODIFIED:20260430T115259Z
UID:10000137-1777892400-1777896000@sfp-alpes.fr
SUMMARY:Giulio FACCHINI (Laboratoire Matière et Systèmes Complexes\, Paris)
DESCRIPTION:Deciphering the origin of saddle-shape geometry in the microstructure of echinoderms skeleton\nRésumé : \nThe microstructure of echinoderms skeleton\, like sea stars and sea urchins\, is an impressive example of self-organization and complexity. This structure called stereom is a porous meshwork\, made of calcite\, whose surface is saddle-shaped\, and remind of minimal surfaces. Minimal surfaces have intrigued scientists for centuries\, as they can spontaneously emerge from minimizing interfacial energy like surface tension. Several studies have addressed the morphogenesis of the stereom\, in sea urchins and other echinoderms\, showing that it forms via the addition of tiny mineral bids at the tip of small skeletal elements that successively branch and bridge to form a complex network. Yet\, a global\, mechanistic\, comprehension of how biomineralizing cells control preferential deposition is still lacking. \nDuring the seminar I will present a recent work1 on the morphogenesis of the particular stereom geometry observed in the sea star P. nodosus. Here\, the stereom can take the form of a diamond Triply Periodic Minimal Surface (TPMS) which confer it specific mechanical properties. Using different marking protocols\, we provide the first experimental insight in the formation of the diamond TPMS stereom\, and show that the formation of such a highly ordered structure relies on a precise and timely coordination of the branching and bridging episodes. Moreover\, we provide experimental evidences of an organic precursor made of F – actin fibers exhibiting saddle-shape geometry. We hypothesise that such a fibers template may self-organise under mechanical tension\, thus explaining the peculiar curvature signature of the final structure. Finally\, I will present some ongoing experimental work performed on sea urchins\, showing that the same morphogenetic mechanism could be shared across very different species. \nContact : emmanuel.siefert@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/giulio-facchini-laboratoire-matiere-et-systemes-complexes-paris/
LOCATION:LiPhy – Salle de conférence\, LiPhy 140 avenue de la Physique\, St Martin d'Hères\, 38402\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260506T110000
DTEND;TZID=Europe/Paris:20260506T120000
DTSTAMP:20260430T140721Z
CREATED:20260430T140156Z
LAST-MODIFIED:20260430T140721Z
UID:10000144-1778065200-1778068800@sfp-alpes.fr
SUMMARY:Tiffany HO (Lab of Prof Brian Wilson at the Princess Margaret Cancer Center\, Toronto\, Canada)
DESCRIPTION:Redefining photodynamic therapy beyond local : Nanoparticle-enabled photodynamic-immune stimulation for treatment of hot and cold cancers\nRésumé : \nPhotodynamic therapy (PDT) is a cancer-treatment modality that\, under the appropriate treatment parameters\, can induce immunogenic tumor cell death and stimulate anti-tumor immunity (photodynamic immune stimulation\, PDIS). This has the potential to prime adaptive immune responses capable of targeting distant\, untreated lesions\, as well as eradicating primary treated tumor. The clinical impact of PDT has been limited by conventional photosensitizers\, which often exhibit poor tumor selectivity and insufficient immune activation. Nanomedicine-based photosensitizer platforms offer a promising strategy to overcome such limitations. Porphysomes (PS)\, a class of all-organic\, multifunctional porphyrin-lipid nanoparticles currently in Phase I clinical trials for positron emission tomography (PET) imaging of metastatic gynecological cancers\, represent one such platform. \nThis seminar will focus on our work investigating PS-PDIS to drive systemic anti-tumor immunity across tumor models of different immunogenicity\, including immunologically “hot” colorectal (CT26) tumors and “cold” melanoma (B16F10) and ovarian (ID8) tumors. The findings establish a strategy to expand PDT beyond localized tumor ablation toward systemic disease control\, including prevention of recurrence and metastasis in cold tumors typically resistant to conventional immunotherapies. The seminar will also highlight ongoing efforts to develop gold nanocluster-based platforms for both light- and radiation-mediated immune stimulation in pancreatic cancer\, further expanding the scope of nanomaterial-enabled photodynamic and radiodynamic immune stimulation. \nThis work was supported by the Terry Fox Research Institute (PPG 1137) and the Government of Canada’s New Frontiers in Research Fund (NFRF) (#NFRFT-2020-00573). » \n_ \nContact : anne-laure.bulin@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/tiffany-ho-lab-of-prof-brian-wilson-at-the-princess-margaret-cancer-center-toronto-canada/
LOCATION:IAB – Salle de séminaire\, IAB Site Santé - Allée des Alpes\, La Tronche\, 38700\, France
CATEGORIES:Séminaire
ORGANIZER;CN="IAB":MAILTO:appaixfl@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260506T113000
DTEND;TZID=Europe/Paris:20260506T123000
DTSTAMP:20260430T120458Z
CREATED:20260430T115832Z
LAST-MODIFIED:20260430T120458Z
UID:10000138-1778067000-1778070600@sfp-alpes.fr
SUMMARY:Adeline LACROIX (Centre for Addiction and Mental Health\, Toronto\, Canada)
DESCRIPTION:Towards an Understanding of Sex Differences in Socio-Emotional Processing in Autism\nRésumé : \nAutism is characterized by persistent difficulties in social interaction and social cognition. These difficulties are partly related to atypical processing of socio-emotional signals\, including emotional facial expressions. Although core autistic characteristics are observed in both males and females\, increasing evidence suggests that autistic females often show a more subtle socio-emotional profile\, marked by greater attention to social stimuli and more typical-appearing social behavior. However\, this profile remains insufficiently characterized\, and the underlying neurobiological mechanisms are still poorly understood.\n\nGiven the central role of face processing in social cognition\, we conducted a series of behavioral and EEG studies to investigate sex differences in autism during face processing at different stages of attentional processing. Our results reveal sex-related differences in autism from early stages of face processing\, with autistic females showing an intermediate profile between autistic males and non-autistic females. Together\, these findings indicate that aggregating males and females may obscure meaningful neurocognitive differences in socio-emotional processing and highlight the need for sex-informed experimental designs and theoretical frameworks in autism research. They further suggest that early differences in socio-emotional processing may contribute to the subtler phenotypic presentation of autism in females.\n_\nContact : michael.pereira@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/adeline-lacroix-centre-for-addiction-and-mental-health-toronto-canada/
LOCATION:GIN – Amphi Serge Kampf\, Grenoble Institut des Neurosciences (GIN) Bât. Edmond J. Safra\, Chemin Fortune Ferrini CHU\, La Tronche\, 38700\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260507T130000
DTEND;TZID=Europe/Paris:20260507T140000
DTSTAMP:20260424T125214Z
CREATED:20260424T125214Z
LAST-MODIFIED:20260424T125214Z
UID:10000133-1778158800-1778162400@sfp-alpes.fr
SUMMARY:Pierre GARCIA (LCB\, Marseille)
DESCRIPTION:When life plays LEGOs : Ancient evolution and extreme diversity of homologous oxidoreductases involved in energy production\n_ \nContact : lucie.lamothe@univ-grenoble-alpes.fr \n 
URL:https://sfp-alpes.fr/event/pierre-garcia-lcb-marseille/
LOCATION:IMAG – Salle de Réunion\, 150 place du Torrent\, St Martin d’Hères\, 38400\, France
CATEGORIES:Séminaire
ORGANIZER;CN="TIMC - IMAG":MAILTO:lucie.lamothe@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260507T140000
DTEND;TZID=Europe/Paris:20260507T150000
DTSTAMP:20260430T122840Z
CREATED:20260430T122734Z
LAST-MODIFIED:20260430T122840Z
UID:10000140-1778162400-1778166000@sfp-alpes.fr
SUMMARY:Amaury PATIN (Expert in Organic Chemistry\, Nestlé Institute of Food Safety & Analytical Sciences (NIFSAS)\, Lausanne\, Suisse)
DESCRIPTION:The Journey of an Organic Chemist : What Organic Chemistry trains you for— From Drug Discovery toFood (Safety)\nRésumé : \nOrganic chemistry plays a central but often under-recognized role in addressing complex industrial challenges that extend well beyond molecule synthesis. In this seminar\, I will describe how training in organic chemistry can be leveraged across multiple industrial domains\, based on my career spanning academia\, biotech\, and industrial research within a multinational food company. \nThe talk presents a personal career journey illustrating the diversity of opportunities available to organic chemists. Starting from doctoral and postdoctoral research in organic chemistry\, I moved into medicinal chemistry within a biotech startup before joining Nestlé Research\, where organic chemistry became a central tool for addressing challenges in ingredient innovation and food safety. \nThrough selected case studies\, I will show how the same fundamental chemical concepts — reactivity\, molecular structure\, metabolism — can be applied in very different contexts\, from drug discovery to food safety. The seminar will also address the evolution from hands-on scientist to project manager and group leader\, highlighting the importance of soft skills such as communication\, interdisciplinarity\, and leadership. \n_ \nContact : sandrine.py@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/amaury-patin-expert-in-organic-chemistry-nestle-institute-of-food-safety-analytical-sciences-nifsas-lausanne-suisse/
LOCATION:DCM – Salle C209\, DCM - Bât Chimie Recherche 301 rue de la Chimie\, St Martin d'Hères\, 38400\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260521T100000
DTEND;TZID=Europe/Paris:20260521T110000
DTSTAMP:20260430T123713Z
CREATED:20260430T123218Z
LAST-MODIFIED:20260430T123713Z
UID:10000141-1779357600-1779361200@sfp-alpes.fr
SUMMARY:Chloé GRAZON (Laboratoire de Chimie des Polymères Organiques (LCPO)\, Université de Bordeaux / CNRS / Bordeaux INP\, Pessac)
DESCRIPTION:Luminescent nanoparticles as bright nanotools for biosensing & bioimaging\nRésumé : à venir \n_ \nContact : galina.dubacheva@univ-grenoble-alpes.fr \n 
URL:https://sfp-alpes.fr/event/chloe-grazon-laboratoire-de-chimie-des-polymeres-organiques-lcpo-universite-de-bordeaux-cnrs-bordeaux-inp-pessac/
LOCATION:DCM – Salle C209\, DCM - Bât Chimie Recherche 301 rue de la Chimie\, St Martin d'Hères\, 38400\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260521T113000
DTEND;TZID=Europe/Paris:20260521T123000
DTSTAMP:20260521T085300Z
CREATED:20260521T085300Z
LAST-MODIFIED:20260521T085300Z
UID:10000152-1779363000-1779366600@sfp-alpes.fr
SUMMARY:Claudie LEMERCIER (Responsable "Associations de patients\, Société et Recherche »\, Délégation Inserm AURA)
DESCRIPTION:Les Associations de Patients et la Recherche\nRésumé : \nLes associations de patients sont un maillon indispensable de notre systèm de santé. Si le financement de projets ou de bourses sont bien connus des chercheurs\, les associations de patients agissent à bien d’autres niveaux qui restent largement méconnus des scientifiques. \nVenez découvrir les actions menées depuis dix ans à la délégation Inserm AuRA pour rapprocher les chercheurs des associations de patients mais également de grand public\, et donner davantage de visibilité aux travaux réalisés dans les laboratoires. La recherche participative en santé sera également abordée. \n_ \nContact : emmanuel.barbier@univ-grenoble-alpes.fr \n  \n  \n 
URL:https://sfp-alpes.fr/event/claudie-lemercier-responsable-associations-de-patients-societe-et-recherche-delegation-inserm-aura/
LOCATION:GIN – Amphi Serge Kampf\, Grenoble Institut des Neurosciences (GIN) Bât. Edmond J. Safra\, Chemin Fortune Ferrini CHU\, La Tronche\, 38700\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260521T133000
DTEND;TZID=Europe/Paris:20260521T163000
DTSTAMP:20260430T124956Z
CREATED:20260430T124859Z
LAST-MODIFIED:20260430T124956Z
UID:10000142-1779370200-1779381000@sfp-alpes.fr
SUMMARY:Soutenance de Thèse de Furhan ABDUL-REZAK (DCM (équipe I2BM) - IAB)
DESCRIPTION:Selective Conjugation of Gold Nanoclusters with Macromolecules: From Functionalization to Assembly\nRésumé : à venir \n_ \nContact : nathalie.camerino@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/soutenance-de-these-de-furhan-abdul-rezak-dcm-equipe-i2bm-iab/
LOCATION:IAB – Salle de séminaire\, IAB Site Santé - Allée des Alpes\, La Tronche\, 38700\, France
CATEGORIES:Soutenance,Soutenance de Thèse
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260526T110000
DTEND;TZID=Europe/Paris:20260526T120000
DTSTAMP:20260424T075655Z
CREATED:20260424T075655Z
LAST-MODIFIED:20260424T075655Z
UID:10000126-1779793200-1779796800@sfp-alpes.fr
SUMMARY:Mark GLOVER (Department of Biochemistry\, University of Alberta\, Edmonton\, Canada)
DESCRIPTION:Mechanism of sRNA recognition and regulation by FinO RNA chaperones\nRésumé : \nThe FinO family of RNA chaperones regulate sRNA function throughout gram negative bacteria. Many of the best characterized family members bind to rho-independent transcription termination structures at the 3’ ends of sRNAs and mediate pairing of the sRNA with their mRNA targets. The crystal structure of the FinO domain of the Legionella pneumophila chaperone RocC bound to its sRNA target reveals a novel interaction that recognizes both the stem and the 3’ end of the terminator structure. The structure suggests a mechanism by which different FinO proteins can selectively bind RNAs with different 3’ tail lengths\, which is likely conserved throughout the FinO family. Biochemical and in vivo studies indicate that intrinsically disordered regions adjacent to the FinO domain are also essential for sRNA regulation\, by remodeling RNA structure to facilitate RNA-RNA association. \n__ \nHôte : Dr Nicolas Coquelle (IBS/Groupe Dynamique et Cinétique des processus moléculaires) \nRappel : L’accès au campus EPN nécessite un avis de rendez-vous. A cet effet merci d’adresser votre demande à ibs.seminaires@ibs.fr (au moins 48h à l’avance).
URL:https://sfp-alpes.fr/event/mark-glover-department-of-biochemistry-university-of-alberta-edmonton-canada/
LOCATION:IBS – Salle des séminaires\, IBS 71 avenue des Martyrs\, Grenoble\, 38042\, France
CATEGORIES:Séminaire
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260528T130000
DTEND;TZID=Europe/Paris:20260528T140000
DTSTAMP:20260521T094049Z
CREATED:20260507T093329Z
LAST-MODIFIED:20260521T094049Z
UID:10000146-1779973200-1779976800@sfp-alpes.fr
SUMMARY:Vincent LACROIX  (LBBE - Lyon)
DESCRIPTION:Repeats : the dark side of transcriptome assembly\n_ \nContact : lucie.lamothe@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/vincent-lacroix-lbbe-lyon/
LOCATION:IMAG – Salle de Réunion\, 150 place du Torrent\, St Martin d’Hères\, 38400\, France
CATEGORIES:Séminaire
ORGANIZER;CN="TIMC - IMAG":MAILTO:lucie.lamothe@univ-grenoble-alpes.fr
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20260528T140000
DTEND;TZID=Europe/Paris:20260528T150000
DTSTAMP:20260430T130828Z
CREATED:20260430T130321Z
LAST-MODIFIED:20260430T130828Z
UID:10000143-1779976800-1779980400@sfp-alpes.fr
SUMMARY:Charles McCRORY (Chemistry and Macromolecular Science and Engineering - University of Michigan\, USA)
DESCRIPTION:Breaking Scaling Relationships in Molecular Electrocatalysts for the CO2 Reduction Reaction\nProfesseur invité UGA du 15/05 au 15/06/2026 \nRésumé : \nFor molecular electrocatalysts\, beneficial decreases in effective overpotential are typically correlated with detrimental decrease in catalytic activity. This scaling relationship arises when both effective overpotential and kinetic reactivity scale with metal site nucleophilicity. Our research strategy is to break typical molecular scaling  relationships by designing molecular electrocatalysts with redox-active ligands where the catalytic reaction is initiated by redox activation of the ligand. These systems decouple metal site nucleophilicity from effective overpotential\, thus allowing us to break the correlation between catalyst reactivity and effective overpotential. \nIn this talk\, we will discuss how incorporating electronic substituents onto the redox-active ligand structure of Co(pyridyldiimine) complexes facilitates ligand reduction and leads to an inverse molecular scaling relationship for electrocatalytic CO2 reduction. We will explore the strategy of incorporating cationic charges into the complex as a means of breaking and inverting scaling relationships both through the incorporation of charged substituents into the ligand scaffold and through construction of homo- and heterobimetallic Co-Co and Co-Zn complexes. We will also discuss whether the activity enhancement from these cationic substituents is best described as\nthrough-space electrostatic stabilization of reactive intermediates\, or through-bond inductive effects related to the stabilization of the catalytic intermediates. Finally\, we will explore how these complexes operate for CO2 reduction and other electrocatalytic reductions when incorporated into larger coordination polymers and macromolecular scaffolds. \n_ \nContact : cyrille.costentin@univ-grenoble-alpes.fr
URL:https://sfp-alpes.fr/event/charles-mccrory-chemistry-and-macromolecular-science-and-engineering-university-of-michigan-usa/
LOCATION:DCM – Salle C209\, DCM - Bât Chimie Recherche 301 rue de la Chimie\, St Martin d'Hères\, 38400\, France
CATEGORIES:Séminaire
END:VEVENT
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